Butcher G D, Winterfield R W, Shapiro D P
Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610.
Avian Dis. 1989 Oct-Dec;33(4):823-6.
A nephropathogenic Massachusetts strain of infectious bronchitis virus, designated H13-IB virus, was isolated from the kidneys of broilers in a commercial flock. Respiratory distress, diarrhea, depression, and high mortality were present. Gross renal lesions consisted of pale coloration, mottling, urate deposition, and swelling. The trachea contained a serous to catarrhal exudate. Microscopically, renal changes were primarily associated with the medullary region. Lesions included an interstitial mononuclear cell infiltration, urate deposition, edema, and degenerative and necrotic tubular changes. Tracheal changes included marked thickening of the mucosa, desquamation of ciliated and glandular epithelia and replacement with a stratified undifferentiated epithelium, and inflammatory cell infiltration.
一种肾致病性马萨诸塞州传染性支气管炎病毒株，命名为H13-IB病毒，从一个商业鸡群的肉鸡肾脏中分离出来。出现了呼吸窘迫、腹泻、抑郁和高死亡率。肾脏大体病变包括颜色苍白、斑驳、尿酸盐沉积和肿胀。气管含有浆液性至卡他性渗出物。显微镜下，肾脏变化主要与髓质区域有关。病变包括间质单核细胞浸润、尿酸盐沉积、水肿以及肾小管的变性和坏死改变。气管变化包括黏膜明显增厚、纤毛和腺上皮脱落并被分层未分化上皮取代以及炎性细胞浸润。
