Sherman David J
INRIA Bordeaux, 351 cours de la Libération, 33405 Talence, France.
N Biotechnol. 2009 Apr;25(4):173-4. doi: 10.1016/j.nbt.2008.12.002. Epub 2008 Dec 30.
In respose to de Marco and colleagues 'Minimum Information for Protein Functional Evaluation,' I observe that they run the risk of imposing a Procrustean solution to the problem of rigorously reporting experimental results involving recombinant proteins. While they rightly identify a need for experimental reporting standards defined by their scientific community, they wrongly assign this role to 'Minimum information' guidelines. In my response I clarify the role and development processes of minimum information standards, and relate a similar experience that we had in the ProteomeBinders Consortium, that led to a distinction between minimum information guidelines for describing a binder and its efficiency as a molecular tool, and the need to define community standards for experimental binder assessment.
针对德马尔科及其同事的《蛋白质功能评估的最低信息要求》，我注意到他们有可能对严格报告涉及重组蛋白的实验结果这一问题采取强求一致的解决方案。虽然他们正确地认识到科学界需要定义实验报告标准，但他们错误地将这一角色赋予了“最低信息”指南。在我的回应中，我阐明了最低信息标准的作用和制定过程，并讲述了我们在蛋白质结合剂联盟中遇到的类似经历，该经历导致了描述结合剂及其作为分子工具的效率的最低信息指南之间的区别，以及定义实验性结合剂评估社区标准的必要性。
