Castle Arthur L, Fiehn Oliver, Kaddurah-Daouk Rima, Lindon John C
Metabolomics and Informatics, National Institute of Diabetes & Digestive & Kidney Diseases, National Institutes of Health (NIH). 6707 Democracy Blvd, Room 791, MSC 5460, Bethesda, Maryland 20892-5460, USA.
Brief Bioinform. 2006 Jun;7(2):159-65. doi: 10.1093/bib/bbl008. Epub 2006 Apr 24.
Informatics standards and controlled vocabularies are essential for allowing information technology to help exchange, manage, interpret and compare large data collections. In a rapidly evolving field, the challenge is to work out how best to describe, but not prescribe, the use of these technologies and methods. A Metabolomics Standards Workshop was held by the US National Institutes of Health (NIH) to bring together multiple ongoing standards efforts in metabolomics with the NIH research community. The goals were to discuss metabolomics workflows (methods, technologies and data treatments) and the needs, challenges and potential approaches to developing a Metabolomics Standards Initiative that will help facilitate this rapidly growing field which has been a focus of the NIH roadmap effort. This report highlights specific aspects of what was presented and discussed at the 1st and 2nd August 2005 Metabolomics Standards Workshop.
信息学标准和受控词汇对于使信息技术能够帮助交换、管理、解释和比较大量数据集合至关重要。在一个快速发展的领域中，挑战在于找出如何最好地描述（而非规定）这些技术和方法的使用。美国国立卫生研究院（NIH）举办了一次代谢组学标准研讨会，将代谢组学中多个正在进行的标准制定工作与NIH研究界汇聚在一起。目标是讨论代谢组学工作流程（方法、技术和数据处理）以及制定代谢组学标准倡议的需求、挑战和潜在方法，该倡议将有助于推动这个快速发展的领域，它一直是NIH路线图工作的重点。本报告重点介绍了2005年8月1日和2日代谢组学标准研讨会上所展示和讨论内容的具体方面。
