Payne R A, Oliver J J, Bain M, Elders A, Bateman D N
Queen's Medical Research Institute, Clinical Pharmacology Unit, University of Edinburgh, 47 Little France Crescent, Edinburgh EH164TJ, UK.
Public Health. 2009 Feb;123(2):134-7. doi: 10.1016/j.puhe.2008.12.002. Epub 2009 Jan 30.
To identify factors influencing hospital re-admission with self-poisoning.
Retrospective cohort follow-up study using national linked hospital discharge data.
All Scottish adult hospital episodes with self-poisoning admissions were captured using NHS Scotland Information Services Division data, and first-time 'index' admissions between 1996 and 2002 were identified. Re-admission rate was defined as the proportion of index admissions who went on to have one or more further self-poisoning admissions within 2 years. The effects of various potential risk factors for re-admission were examined using logistic regression.
In total, 50,891 index admissions were identified; of these, 8278 patients were re-admitted. The 1-year re-admission rate was 12.2%. Older patients (>65 years) were least likely to be re-admitted [odds ratio (OR) 0.40, P<0.01, compared with patients aged 15-24 years]. No differences were found between males and females. Previous psychiatric hospital admission was associated with an increased re-admission rate (OR 2.85, P<0.01), with a diagnosis of personality disorder associated with the highest rate of re-admission (OR 4.59, P<0.01). Other factors predicting re-admission were: increased deprivation (quintile 3: OR 1.16, P<0.01; quintile 5: OR 1.15, P<0.01, compared with quintile 1); taking medicines for chronic disease, drug dependency (OR 1.6 and 1.19, P < or = 0.02) or antidepressants (OR 1.11, P=0.01) (compared with paracetamol); and co-ingestion of three or more agents (OR 1.37, P<0.01).
Younger age, higher deprivation, ingestion of certain drug groups or multiple drug types, and prior psychiatric hospital admission are all risk factors for re-admission with self-poisoning. Personality disorder carried the greatest risk of re-admission. These findings may provide a basis to develop policies to reduce re-admission rates in the future.
确定影响因自我中毒而再次入院的因素。
使用全国性的关联医院出院数据进行回顾性队列随访研究。
利用苏格兰国民保健服务信息服务部的数据,收集所有苏格兰成年患者因自我中毒而入院的情况,并确定1996年至2002年期间的首次“索引”入院病例。再入院率定义为在2年内继续有一次或多次因自我中毒而再次入院的索引入院病例的比例。使用逻辑回归分析各种潜在再入院风险因素的影响。
总共确定了50891例索引入院病例;其中,8278例患者再次入院。1年再入院率为12.2%。老年患者(>65岁)再次入院的可能性最小[比值比(OR)为0.40,P<0.01,与15-24岁患者相比]。男性和女性之间未发现差异。既往有精神病医院住院史与再入院率增加相关(OR为2.85,P<0.01),人格障碍诊断与最高再入院率相关(OR为4.59,P<0.01)。其他预测再入院的因素包括:贫困程度增加(第3五分位数:OR为1.16,P<0.01;第5五分位数:OR为1.15,P<0.01,与第1五分位数相比);服用慢性疾病药物、药物依赖(OR分别为1.6和1.19,P≤0.02)或抗抑郁药(OR为1.11,P=0.01)(与对乙酰氨基酚相比);以及同时摄入三种或更多药物(OR为1.37,P<0.01)。
年龄较小、贫困程度较高、摄入某些药物类别或多种药物类型以及既往有精神病医院住院史均是因自我中毒而再次入院的风险因素。人格障碍的再入院风险最大。这些发现可能为未来制定降低再入院率的政策提供依据。