Sorge M, Weidhase L, Bernhard M, Gries A, Petros S
Medical Intensive Care Unit, University Hospital Leipzig, Liebigstr. 20, 04103, Leipzig, Germany.
Anaesthesist. 2015 Jun;64(6):456-62. doi: 10.1007/s00101-015-0030-x.
To describe the trend of acute self-poisoning in the emergency and intensive care.
Electronic charts of adults who presented to the emergency department of the University Hospital Leipzig with self-poisoning following a suicide attempt (suicide group), intoxication (intoxication group), drug overdose for relief of pain or discomfort (drug overdose group) between 2005 and 2012 were analyzed.
3533 adults (62.6% males) were identified, with the yearly admissions increasing from 305 in 2005 to 624 in 2012. The admission rate in relation to the total emergency department admissions also increased, from 1.2% in 2005 to 1.9% in 2012. 31.7% of the patients were younger than 25 years. The reasons for self-poisoning were suicide attempt (18.1%), intoxication (76.8%) and drug overdose (2.9%). The reason could not be clearly classified in 80 patients. Psychotropic drugs were used in 71.6% of suicide attempts, while alcohol was the sole cause of intoxication in 80.1% of cases in the intoxication group. Self-poisoning using at least two substances was observed in 52.0% of the suicide attempts, 10.3% of those with intoxication and 29.7% of those with drug overdose. While alcohol remains the most common cause of intoxication, there was a drastic increase in the consumption of cannabinoids, Crystal Meth and gamma-hydroxybutyrate in the years 2011 and 2012. ICU admission was necessary in 16.6% of the cases. There were 22 deaths (0.6% of the study population), of whom 15 were in the suicide group (2.3%), four (0.15%) in the intoxication group, and three in the not clearly classified group (3.8%).
Acute self-poisoning is an increasing medical issue. Psychotropic drugs remain the most common means of suicide attempt. Although alcohol intoxication is very frequent, intake of illicit drugs as the cause of emergency admission is increasing.
描述急诊和重症监护中急性自我中毒的趋势。
分析了2005年至2012年间因自杀未遂(自杀组)、中毒(中毒组)、为缓解疼痛或不适而药物过量(药物过量组)到莱比锡大学医院急诊科就诊的成年人的电子病历。
共识别出3533名成年人(62.6%为男性),年入院人数从2005年的305人增加到2012年的624人。相对于急诊科总入院人数的入院率也有所增加,从2005年的1.2%增至2012年的1.9%。31.7%的患者年龄小于25岁。自我中毒的原因有自杀未遂(18.1%)、中毒(76.8%)和药物过量(2.9%)。80名患者的原因无法明确分类。71.6%的自杀未遂者使用了精神药物,而在中毒组中,80.1%的病例酒精是中毒的唯一原因。52.0%的自杀未遂者、10.3%的中毒者和29.7%的药物过量者使用了至少两种物质。虽然酒精仍然是中毒最常见的原因,但2011年和2012年大麻素、冰毒和γ-羟基丁酸的消耗量急剧增加。16.6%的病例需要入住重症监护病房。有22例死亡(占研究人群的0.6%),其中15例在自杀组(2.3%),4例在中毒组(0.15%),3例在未明确分类组(3.8%)。
急性自我中毒是一个日益严重的医学问题。精神药物仍然是最常见的自杀未遂手段。虽然酒精中毒很常见,但作为急诊入院原因的非法药物摄入正在增加。