Venza Mario, Visalli Maria, Lo Giudice Giuseppe, Cicciù Marco, Passi Pietro, Teti Diana
Department of Odontostomatology, University of Messina, Messina, Italy.
J Periodontol. 2009 Feb;80(2):297-306. doi: 10.1902/jop.2009.080411.
Endosseous dental titanium implants have revolutionized restorative dentistry and have made a significant impact on improved patient care. The aim of this study was to compare and evaluate the influence of the placement technique on periodontal health.
A baseline examination was performed in patients with submerged and non-submerged titanium implants, including an evaluation of plaque index (PI), gingival index (GI), periodontal probing depth (PD), clinical attachment level (CAL), and bone level, as well as histamine and arachidonic acid metabolite concentrations, in the peri-implant crevicular fluid. Examinations were repeated after 12, 24, and 36 months.
Bone loss was significantly higher in the submerged group relative to the non-submerged group at 3 years (P <0.01), with a slight increase at 24 months. All clinical parameters were significantly higher in the submerged group relative to the non-submerged group at 24 and 36 months (P <0.05 for PI; P <0.01 for GI, PD, and CAL). The mean levels of histamine and other inflammatory mediators were significantly higher, whereas 15(S)-hydroxy-5,8,11,13-eicosatetraenoic acid concentrations were significantly reduced in the submerged group, with a high correlation with periodontal indices at 24 and 36 months (P <0.001).
This longitudinal study suggested that submerged implants present a number of risks for periodontal complications compared to non-submerged implants, which can be evidenced by inflammatory mediator variations in the peri-implant crevicular fluid.
骨内牙钛种植体彻底改变了修复牙科，并对改善患者护理产生了重大影响。本研究的目的是比较和评估种植技术对牙周健康的影响。
对植入了潜入式和非潜入式钛种植体的患者进行基线检查，包括评估菌斑指数（PI）、牙龈指数（GI）、牙周探诊深度（PD）、临床附着水平（CAL）和骨水平，以及种植体周围龈沟液中的组胺和花生四烯酸代谢物浓度。在12、24和36个月后重复检查。
3年后，潜入式种植组的骨吸收明显高于非潜入式种植组（P<0.01），在24个月时略有增加。在24和36个月时，潜入式种植组的所有临床参数均明显高于非潜入式种植组（PI，P<0.05；GI、PD和CAL，P<0.01）。潜入式种植组中组胺和其他炎症介质的平均水平明显更高，而15(S)-羟基-5,8,11,13-二十碳四烯酸浓度明显降低，并且在24和36个月时与牙周指数高度相关（P<0.001）。
这项纵向研究表明，与非潜入式种植体相比，潜入式种植体存在许多牙周并发症风险，这可以通过种植体周围龈沟液中炎症介质的变化得到证实。
