Dutta P, Bhattacharya S K, Dutta D, Mitra U, Bhattacharya M K, Rasaily R, Sen D, Saha M R, Mukherjee A, Pal S C
Division of Clinical Medicine, National Institute of Cholera and Enteric Diseases, Calcutta, India.
J Diarrhoeal Dis Res. 1991 Jun;9(2):118-22.
The safety and efficacy of standard oral glucose-electrolyte solution, containing 90 mmol of sodium per litre, was evaluated in the treatment of dehydrating diarrhoea among severely malnourished (marasmic) children. A total of 81 male children aged between 6 and 48 months were studied; 41 were in the malnourished group (study group: less than 60% of Harvard Standard weight-for-age) and 40 were in the well-nourished group (control group: 80% or more Harvard Standard weight-for-age). Children of both groups could be rehydrated with standard oral rehydration solution (ORS) without encountering any clinical or biochemical complications. The results of this study lend support to the World Health Organization's concept of a unified formula of ORS for the treatment of all cases of acute diarrhoea, including severely malnourished children.
对每升含90毫摩尔钠的标准口服葡萄糖电解质溶液治疗重度营养不良（消瘦型）儿童脱水腹泻的安全性和有效性进行了评估。共研究了81名年龄在6至48个月之间的男童；41名属于营养不良组（研究组：低于哈佛标准年龄别体重的60%），40名属于营养良好组（对照组：为哈佛标准年龄别体重的80%或更高）。两组儿童均可用标准口服补液盐（ORS）进行补液，未出现任何临床或生化并发症。本研究结果支持世界卫生组织关于用统一配方的ORS治疗包括重度营养不良儿童在内的所有急性腹泻病例的理念。
