Flegal Katherine M, Graubard Barry I
National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD 20782, USA.
Am J Clin Nutr. 2009 Apr;89(4):1213-9. doi: 10.3945/ajcn.2008.26698. Epub 2009 Feb 3.
Estimates of excess mortality associated with body mass index (BMI; in kg/m(2)) have been calculated for the US population.
The objective of this article is to compare the excess mortality associated with BMI levels to the excess mortality associated with other anthropometric variables.
For the 1988-1994 Third National Health and Nutrition Examination Survey, estimates of excess deaths were calculated for standard BMI levels and for comparable levels of percentage body fat, waist circumference, hip and arm circumferences, waist-hip ratio, the sum of 4 skinfold thicknesses, and waist-stature ratio. The outcome measure is the percentage of deaths in the full sample in excess of those predicted for the reference category.
For the level equivalent to BMI <18.5, estimates of excess deaths ranged from 0.3% for waist-hip ratio to 2.4% for percentage body fat. All except waist circumference, waist-hip ratio, and waist-stature ratio were significantly greater than zero (P < 0.05). For the level equivalent to BMI 25 to <30, the percentage of excess deaths was 0.1% for percentage body fat and negative for all other variables; estimates were significantly below zero only for circumferences and waist-stature ratio. For the level equivalent to BMI > or = 30, estimates ranged from -1.7% for waist circumference to 1.5% for percentage of fat; none were significantly different from zero. Estimates for all-cause mortality, obesity-related causes of death, and other causes of death showed no statistically significant or systematic differences between BMI and other variables.
In this population-based study, attributable fractions of deaths were similar across measures.
已针对美国人群计算了与体重指数(BMI;单位:kg/m²)相关的超额死亡率。
本文的目的是比较与BMI水平相关的超额死亡率和与其他人体测量变量相关的超额死亡率。
对于1988 - 1994年第三次全国健康和营养检查调查,计算了标准BMI水平以及身体脂肪百分比、腰围、臀围和臂围、腰臀比、4处皮褶厚度之和以及腰高比等可比水平的超额死亡估计值。结局指标是全样本中死亡人数超过参考类别预测死亡人数的百分比。
对于相当于BMI <18.5的水平,超额死亡估计值范围从腰臀比的0.3%到身体脂肪百分比的2.4%。除腰围、腰臀比和腰高比外,所有估计值均显著大于零(P < 0.05)。对于相当于BMI 25至<30的水平,身体脂肪百分比的超额死亡百分比为0.1%,其他所有变量的超额死亡百分比为负值;仅周长和腰高比的估计值显著低于零。对于相当于BMI≥30的水平,估计值范围从腰围的 - 1.7%到脂肪百分比的1.5%;均与零无显著差异。全因死亡率、肥胖相关死因和其他死因的估计值在BMI与其他变量之间未显示出统计学上的显著差异或系统性差异。
在这项基于人群的研究中,各测量指标的死亡归因比例相似。