通过血液透析中的透析内生物电阻抗分析有效测定干体重

Effective determination of dry weight by intradialytic bioimpedance analysis in hemodialysis.

作者信息

Chongthanakorn Kamonrat, Tiranathanagul Khajohn, Susantitaphong Paweena, Praditpornsilpa Kearkiat, Eiam-Ong Somchai

机构信息

Division of Nephrology, Department of Medicine, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, Thailand.

出版信息

Blood Purif. 2009;27(3):235-41. doi: 10.1159/000199428. Epub 2009 Feb 4.

DOI:10.1159/000199428

PMID:19190396

Abstract

BACKGROUND

The new dry weight (DW) assessment technique by intradialytic sequential bioimpedance analysis (BIA) was evaluated in this study.

METHODS

Intradialytic changes in the ratio of resistance at baseline per each time point (R(0)/R(t)) determined by a total body single-frequency BIA were recorded in 19 hemodialysis patients. The bioimpedance DW (BIADW) could be drawn from a time point at which R(0)/R(t) was constant.

RESULTS

After the first session where the previous DW was prescribed, the participants could be divided into 2 groups: the under BIADW and over BIADW groups. In the under BIADW group, the BIADW was achieved earlier than the previous DW. The intradialytic symptoms disappeared without changes in the home-monitored mean blood pressure and antihypertensive agents at 1-month follow-up. In the over BIADW group, the BIADW could be obtained in the following sessions and the prescribed DW could be gradually reduced. The home-monitored mean blood pressure was decreased and the numbers of antihypertensive drugs were reduced.

CONCLUSION

Intradialytic single-frequency BIA assessment can be used as a tool to accurately determine the DW.

摘要

背景

本研究评估了通过透析中序贯生物电阻抗分析（BIA）进行新的干体重（DW）评估技术。

方法

记录了19例血液透析患者通过全身单频BIA测定的每个时间点基线电阻抗比值（R(0)/R(t)）在透析过程中的变化。生物电阻抗干体重（BIADW）可从R(0)/R(t)恒定的时间点得出。

结果

在首次设定先前干体重的透析 session 后，参与者可分为两组：低于BIADW组和高于BIADW组。在低于BIADW组中，BIADW比先前的干体重更早达到。在1个月的随访中，透析中的症状消失，家庭监测的平均血压和降压药物无变化。在高于BIADW组中，在随后的透析 session 中可获得BIADW，且设定的干体重可逐渐降低。家庭监测的平均血压降低，降压药物数量减少。