Pierce Samuel R, Lauer Richard T, Prosser Laura A, Mohamed Feroze B, Dougherty Jaimie B, Faro Scott H, Betz Randall R
Research Department, Shriners Hospitals for Children in Philadelphia, Philadelphia, Pennsylvania 19140, USA.
Am J Phys Med Rehabil. 2009 Apr;88(4):275-7. doi: 10.1097/PHM.0b013e318198b536.
Incidental findings during fMRI: ethical and procedural issues.This purpose of this report was to describe the discovery of an incidental finding during functional magnetic resonance imaging in a child of typical development. During the completion of a functional magnetic resonance imaging protocol, an abnormality was noted by a board-certified neuroradiologist that was identified as a benign developmental arachnoid pouch. Significant ethical concerns were apparent with the discovery of an incidental finding, which included how to address the likelihood of incidental findings in the consent and assent process, how to disclose the incidental findings to the subject's parents and primary care provider, and how to minimize subject and parental anxiety.
伦理与程序问题。本报告的目的是描述在一名发育正常儿童的功能磁共振成像检查过程中偶然发现的情况。在完成一项功能磁共振成像检查方案时，一位获得委员会认证的神经放射科医生发现了一个异常，经鉴定为良性发育性蛛网膜囊肿。偶然发现的情况引发了重大的伦理问题，包括在同意和赞成过程中如何应对偶然发现的可能性、如何向受试者的父母和初级保健提供者披露偶然发现的情况，以及如何尽量减少受试者和父母的焦虑。
