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1986年北九州市肠道病毒7型流行——污水病毒分离及儿童血清流行病学调查

[Epidemic of echovirus type 7 in Kitakyushu City in 1986--a survey of isolation of viruses from the sewage and seroepidemiology of children].

作者信息

Nashida M, Shimohara E, Sugishima S

机构信息

Kitakyushu Municipal Institute of Environmental Health Sciences.

出版信息

Kansenshogaku Zasshi. 1991 Jun;65(6):725-9. doi: 10.11150/kansenshogakuzasshi1970.65.725.

Abstract

In 1986, under the Infectious Disease Surveillance system in Fukuoka Prefecture, no isolation of echovirus type 7 from aseptic meningitis patients were reported. It was unclear that epidemics of this virus occurred in Fukuoka Prefecture, including Kitakyushu City. We tried to isolate enteric viruses from the sewage (activated sludges) in Kitakyushu City in 1986. Outbreaks of isolations of echovirus type 7 started in September and continued until in December. This result suggested that echovirus type 7 caused epidemic during this period in Kitakyushu City. Sera were collected from children in 1989, and were examined neutralizing antibody titer against echovirus type 7. Antibody titers were positive in the sera of about half of children above 1 year of age in 1986. From results of virus isolations from the sewage and serological study, it was confirmed that echovirus type 7, reported no isolation in Fukuoka Prefectural surveillance system, caused epidemics in Kitakyushu City in 1986.

摘要

1986年,在福冈县的传染病监测系统下,未报告从无菌性脑膜炎患者中分离出7型艾柯病毒。尚不清楚包括北九州市在内的福冈县是否发生过这种病毒的流行。1986年,我们试图从北九州市的污水(活性污泥)中分离肠道病毒。7型艾柯病毒的分离疫情始于9月,一直持续到12月。这一结果表明,7型艾柯病毒在这段时间内在北九州市引起了流行。1989年从儿童中采集血清,并检测针对7型艾柯病毒的中和抗体滴度。1986年,1岁以上儿童约一半的血清中抗体滴度呈阳性。从污水病毒分离结果和血清学研究结果来看,证实了在福冈县监测系统中未报告分离情况的7型艾柯病毒,于1986年在北九州市引起了流行。

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