纳米颗粒增强的潜指纹荧光成像揭示药物滥用情况。
Nanoparticle-enhanced fluorescence imaging of latent fingerprints reveals drug abuse.
作者信息
Wolfbeis Otto S
机构信息
Institute of Analytical Chemistry, Chemo- and Biosensors, University of Regensburg, 93040 Regensburg, Germany.
出版信息
Angew Chem Int Ed Engl. 2009;48(13):2268-9. doi: 10.1002/anie.200805765.
PMID:19191362
Abstract
No sweat! The sweat in a latent fingerprint (LFP) can contain orally ingested drugs and their metabolites. In a new method for drug detection, primary antibodies (Abs) against drug metabolites are conjugated to magnetic nanoparticles (NPs). The LFP is incubated with the NPs, excess particles removed, and the LFP treated with a fluorescently labeled secondary antibody. Fluorescence imaging then allows characterization.
摘要
没问题！潜在指纹（LFP）中的汗液可能含有口服摄入的药物及其代谢物。在一种新的药物检测方法中，针对药物代谢物的一抗（Abs）与磁性纳米颗粒（NPs）结合。将LFP与NPs一起孵育，去除多余的颗粒，然后用荧光标记的二抗处理LFP。然后通过荧光成像进行表征。
Zotero 插件