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对氟喹诺酮类药物和链霉素耐药但对二线注射治疗敏感的耐多药结核病,其预后比广泛耐药结核病更好。

Multidrug-resistant tuberculosis (TB) resistant to fluoroquinolones and streptomycin but susceptible to second-line injection therapy has a better prognosis than extensively drug-resistant TB.

作者信息

Chan Edward D, Strand Matthew J, Iseman Michael D

机构信息

Department of Medicine, National Jewish Health, Denver, CO 80206, USA.

出版信息

Clin Infect Dis. 2009 Mar 1;48(5):e50-2. doi: 10.1086/597010.

Abstract

Multidrug-resistant tuberculosis (TB) strains resistant to the fluoroquinolones and streptomycin but susceptible to second-line injection treatment would not be defined as extensively drug-resistant TB. In a cohort of 174 patients with multidrug-resistant TB, we demonstrated that 12 patients with multidrug-resistant TB strains resistant to the fluoroquinolones and streptomycin had significantly better initial and long-term outcomes, compared with 10 patients with extensively drug-resistant TB.

摘要

对氟喹诺酮类和链霉素耐药但对二线注射治疗敏感的耐多药结核病(TB)菌株,不应被定义为广泛耐药结核病。在一组174例耐多药结核病患者中,我们证明,与10例广泛耐药结核病患者相比,12例对氟喹诺酮类和链霉素耐药的耐多药结核病患者的初始和长期预后明显更好。

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