Zbaeren P, Lehmann W, Widgren S
Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Geneva, Switzerland.
J Laryngol Otol. 1991 Sep;105(9):782-5. doi: 10.1017/s0022215100117323.
The occurrence of acinic cell carcinoma in the minor salivary glands appears to be exceptional. A review of the English language literature revealed about 80 previously reported cases. In this paper, the clinical behaviour and pathological findings in three cases are reported. The tumours took their origin from the hard palate, soft palate and lower lip. The three cases presented with malignant clinical behaviour; all three recurred. In one case the local recurrence was multinodular with capsular infiltration. Two cases developed regional lymph node metastasis, and one metastasized to the lung and liver. In one the tumour infiltrated bony structures, and nerve in another. These cases tend to support the belief of some authors that acinic cell 'tumours' are clinically malignant and should be included in the carcinoma group.
小唾液腺腺泡细胞癌的发生似乎很罕见。对英文文献的回顾发现了约80例先前报道的病例。本文报告了3例的临床行为和病理结果。肿瘤分别起源于硬腭、软腭和下唇。这3例均表现出恶性临床行为；全部复发。1例局部复发为多结节状伴包膜浸润。2例发生区域淋巴结转移，1例转移至肺和肝。1例肿瘤侵犯骨质结构，另1例侵犯神经。这些病例倾向于支持一些作者的观点，即腺泡细胞“肿瘤”在临床上具有恶性，应归入癌组。
