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人类偏瘫性痉挛中放松的小腿三头肌反射兴奋性双侧变化的时间进程。

The time-course of bilateral changes in the reflex excitability of relaxed triceps surae muscle in human hemiparetic spasticity.

作者信息

Thilmann A F, Fellows S J

机构信息

Neurologische Klinik mit klinischer Neurophysiologie, Alfried Krupp Krankenhaus, Essen, Federal Republic of Germany.

出版信息

J Neurol. 1991 Aug;238(5):293-8. doi: 10.1007/BF00319742.

DOI:10.1007/BF00319742
PMID:1919613
Abstract

Short, rapid dorsiflexion of the normal human ankle induces a single, synchronised reflex EMG response in the initially relaxed triceps surae muscle (TS). In subjects in whom hemiparesis is present as a result of a unilateral ischaemic cerebral lesion, a reflex EMG response can be elicited on either side with timing identical to that of the normal response. The magnitude of the response in hemiparetic subjects, however, differs from the normal on both the side contralateral and that ipsilateral to the causative lesion. Furthermore, the magnitude of this response varies over the time-course of spasticity. Contralaterally to the lesion, a gradual increase in the magnitude of the response to imposed displacement occurs. One year after stroke, the response has reached a level significantly larger than normal. Changes in the magnitude of the contralateral Achilles tendon jerk reflex EMG are apparent earlier than changes in the response to imposed displacement, with exaggerated tendon jerks already being apparent between 1 and 3 months after stroke. On the side ipsilateral to the lesion, a profound depression of the response to imposed displacement is visible as early as a month after stroke. This depression diminishes over the 1st year, but the response has not even then returned to normal values. These changes are not reflected in the ipsilateral tendon jerk response, which remains normal throughout this period.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

正常人体踝关节的快速短时间背屈会在最初放松的小腿三头肌(TS)中诱发单一、同步的反射性肌电图反应。在因单侧缺血性脑损伤而出现偏瘫的受试者中,两侧均可引出反射性肌电图反应,其时间与正常反应相同。然而,偏瘫受试者两侧的反应幅度与正常情况不同,与致病损伤对侧和同侧均不同。此外,这种反应的幅度在痉挛的病程中会发生变化。在损伤对侧,对施加位移的反应幅度会逐渐增加。中风一年后,该反应达到明显高于正常的水平。对侧跟腱反射肌电图反应幅度的变化比对施加位移反应的变化更早出现,中风后1至3个月时腱反射亢进就已明显。在损伤同侧,对施加位移的反应早在中风后一个月就可见到明显降低。这种降低在第一年逐渐减轻,但即使那时反应仍未恢复到正常水平。这些变化在同侧腱反射反应中未得到体现,在此期间同侧腱反射反应一直保持正常。(摘要截断于250字)

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