Alonso E, Gilsanz F, Gredilla E, Martínez B, Canser E, Alsina E
Department of Anesthesia and Reanimation, La Paz Maternal University Hospital, Madrid, Spain.
Int J Obstet Anesth. 2009 Apr;18(2):137-41. doi: 10.1016/j.ijoa.2008.11.001. Epub 2009 Feb 3.
Few studies have assessed the efficacy and safety of continuous spinal anesthesia in obstetrics, although placement of a catheter in the intrathecal space theoretically offers advantages in these patients.
Ninety-two women scheduled for elective cesarean delivery using continuous spinal anesthesia with the catheter-over-needle technique (22- or 24-gauge Spinocath) were included in the study. The doses of local anesthetic used, hemodynamic variables, use of ephedrine and other drugs, and incidence of complications such as technical failure and postdural puncture headache (PDPH) were recorded.
The mean (+/-SD) dose of hyperbaric bupivacaine used was 8.2+/-1.8 mg. The incidence of hypotension was 30% and the mean total dose of ephedrine was 4+/-7 mg. The continuous spinal anesthetic technique failed in 18 women (20%). The overall incidence of post-dural-puncture headache was 29%; 18% of patients with post-dural-puncture headache required a blood patch.
Compared to previous reports, the incidence of block failure and PDPH in this study was unacceptably high and therefore the risks of the technique appear to outweigh the advantages of continuous spinal anesthesia in obstetric practice.
尽管理论上在鞘内间隙放置导管对产科患者有优势,但很少有研究评估连续脊麻在产科中的有效性和安全性。
本研究纳入了92例计划采用针内导管技术(22号或24号Spinocath)进行连续脊麻的择期剖宫产妇女。记录所用局部麻醉药的剂量、血流动力学变量、麻黄碱及其他药物的使用情况,以及技术失败和腰穿后头痛(PDPH)等并发症的发生率。
所用重比重布比卡因的平均(±标准差)剂量为8.2±1.8mg。低血压发生率为30%,麻黄碱的平均总剂量为4±7mg。18例妇女(20%)连续脊麻技术失败。腰穿后头痛的总体发生率为29%;18%的腰穿后头痛患者需要进行血补丁治疗。
与先前的报告相比,本研究中阻滞失败和腰穿后头痛的发生率高得令人无法接受,因此在产科实践中,该技术的风险似乎超过了连续脊麻的优势。