生活在安纳托利亚中部的土耳其患者中ST段抬高型心肌梗死危险因素的患病率。

Prevalence of risk factors of ST segment elevation myocardial infarction in Turkish patients living in Central Anatolia.

作者信息

Aygül Nazif, Ozdemir Kurtuluş, Abaci Adnan, Aygül Meryem Ulkü, Düzenli Mehmet Akif, Vatankulu Mehmet Akif, Yazici Hüseyin Uğur, Ozdoğru Ibrahim, Karakaya Ekrem

机构信息

Department of Cardiology, Meram Medical Faculty, Selçuk University, Konya, Turkey.

出版信息

Anadolu Kardiyol Derg. 2009 Feb;9(1):3-8.

PMID:19196566

Abstract

OBJECTIVE

There is not enough available data in our country about the prevalence of risk factors for ST-elevation myocardial infarction (STEMI), which has the highest in-hospital mortality rate within subtypes of acute coronary syndromes. Therefore, in this study, we aimed to evaluate the prevalence of risk factors for STEMI in Central Anatolia, one of the regions with high risk for coronary heart disease (CHD).

METHODS

This cross-sectional observational study included 1210 patients (962 men, 248 women) with the diagnosis of STEMI in 3 tertiary-medical centers in 3 cities in Central-Anatolia (Ankara, Konya, and Kayseri). Demographic characteristics (age, gender) and risk factors known to be traditional risk factors for CHD (history of hypertension (HT), diabetes mellitus (DM), smoking, and family history) were inquired and fasting blood samples within 24 hours from onset of STEMI were taken to analyze lipid levels. Patients were divided into 3 groups based on their ages: Group A--age = or <44 years; Group B--age 45-64 years; and Group C--age = or >65 years. Prevalence of risk factors and differences within age-groups and genders were evaluated.

RESULTS

The mean age was 58+/- 11 years (range 24-96 years). Although the percentage of female patients increased in relation to increasing age, 80% of the total patients were male. While prevalence of smoking and family history was observed to decrease with aging, there was a statistically significant increase in prevalence of HT and DM (p<0.001). Prevalence of smoking was the highest in young patients and males (p<0.001). Prevalence of HT and DM, on the other hand, was significantly higher in women than in men (p<0.001). Although the number of modifiable risk factors was found to be significantly smaller in men, male patients with STEMI were 8 years younger than females on average.

CONCLUSIONS

The results of our study, in which modifiable risk factors and especially smoking were found to have a high prevalence in patients with STEMI living in Central Anatolia, suggested that most STEMI cases especially at younger ages might be prevented by the modification of these risk factors.

摘要

目的

我国关于ST段抬高型心肌梗死（STEMI）危险因素患病率的可用数据不足，而STEMI在急性冠脉综合征亚型中院内死亡率最高。因此，在本研究中，我们旨在评估安纳托利亚中部地区（冠心病（CHD）高风险地区之一）STEMI危险因素的患病率。

方法

这项横断面观察性研究纳入了安纳托利亚中部3个城市（安卡拉、科尼亚和开塞利）的3家三级医疗中心诊断为STEMI的1210例患者（962例男性，248例女性）。询问人口统计学特征（年龄、性别）以及已知的CHD传统危险因素（高血压（HT）病史、糖尿病（DM）病史、吸烟和家族史），并在STEMI发病后24小时内采集空腹血样以分析血脂水平。患者按年龄分为3组：A组——年龄≤44岁；B组——年龄45 - 64岁；C组——年龄≥65岁。评估危险因素的患病率以及年龄组和性别之间的差异。

结果

平均年龄为58±11岁（范围24 - 96岁）。尽管女性患者的比例随年龄增长而增加，但患者总数的80%为男性。虽然观察到吸烟和家族史的患病率随年龄增长而降低，但HT和DM的患病率有统计学显著增加（p<0.001）。吸烟患病率在年轻患者和男性中最高（p<0.001）。另一方面，HT和DM的患病率在女性中显著高于男性（p<0.001）。虽然发现男性可改变危险因素的数量明显较少，但STEMI男性患者的平均年龄比女性小8岁。