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关于宫颈癌患者单纯疱疹病毒2型(HSV - 2)抗体证据的研究(作者译)

[Investigations concerning the evidence of herpes simplex virus type 2 (HSV-2) antibodies in patients with carcinoma of the cervix (author's transl)].

作者信息

Dostal V, Fanta D, Reiss-Gutfreund R J, Janisch H, Berger R

出版信息

Wien Klin Wochenschr. 1977 Mar 18;89(6):201-3.

PMID:191994
Abstract

The neutralizing antibodies to HSV-1 and HSV-2 were determined in the sera of 128 patients. Infection was detectable in nearly 100% of the cases in each of the three investigated groups (patients with carcinoma of the cervix, female patients with chronic recurrent HSV infection in the genital area and a control group without and history of HSV infection). The percentage of patients displaying HSV-2 antibodies in the group with carcinoma of the cervix (38%) is significantly higher than in the control group (12%). The results are compared with the findings of other authors and the possible causal significance of HSV in carcinogenesis is discussed.

摘要

在128名患者的血清中检测了针对单纯疱疹病毒1型(HSV-1)和单纯疱疹病毒2型(HSV-2)的中和抗体。在三个被调查的组(宫颈癌患者、生殖器区域患有慢性复发性HSV感染的女性患者以及无HSV感染病史的对照组)中,几乎100%的病例都可检测到感染。宫颈癌组中出现HSV-2抗体的患者百分比(38%)显著高于对照组(12%)。将结果与其他作者的研究结果进行了比较,并讨论了HSV在致癌过程中可能的因果关系。

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