Hirano Ken, Aoyagi Masaru, Ishido Tomomi, Ooie Toshihiko, Frusawa Hiroshi, Asakawa Masumi, Shimizu Toshimi, Ishikawa Mitsuru
Health Technology Research Center, National Institute of Advanced Industrial Science and Technology, 2217-14, Hayashi-cho, Takamatsu, Kagawa, 761-0395, Japan.
Anal Chem. 2009 Feb 15;81(4):1459-64. doi: 10.1021/ac8022795.
The present work addresses the length distribution of self-assembled lipid nanotubes (LNTs) by controlling the orientation of the LNTs using an alternating current (ac) electric field in aqueous solutions. The effect of the ac field on the orientation and rotation of individual LNTs was examined to evaluate the optimum orientation frequency by visualizing the individual LNTs in real time. By using the high-frequency ac field, we have successfully measured the length distribution for two different types of LNTs and have quantitatively analyzed the maximum occurrences of the length distribution as well as the extension of the longer length region.
本研究通过在水溶液中使用交变电场（ac）控制脂质自组装纳米管（LNTs）的取向，来探讨LNTs的长度分布。通过实时观察单个LNTs，研究了交流电场对单个LNTs取向和旋转的影响，以评估最佳取向频率。利用高频交流电场，我们成功测量了两种不同类型LNTs的长度分布，并对长度分布的最大出现次数以及较长长度区域的延伸进行了定量分析。
