寡糖药物的固相合成：综述
Solid-phase synthesis of oligosaccharide drugs: a review.
作者信息
Dhanawat Meenakshi, Shrivastava Sushant Kumar
机构信息
Department of Pharmaceutics, Institute of Technology, Banaras Hindu University Varanasi, -22100, India.
出版信息
Mini Rev Med Chem. 2009 Feb;9(2):169-85. doi: 10.2174/138955709787316083.
Solid- phase synthesis is an approach, where synthetic transformation in carbohydrates are carried out with one of the reactant molecule attached to an insoluble material referred as polymeric support via linker. In recent years, it has been extensively accepted as fast and accurate method for the synthesis of biologically active oligosaccharides. This review attempts to focus on various methods of oligosaccharide synthesis by solid- phase including their applications.
固相合成是一种方法，即碳水化合物中的合成转化是在其中一种反应物分子通过连接基连接到称为聚合物载体的不溶性材料上进行的。近年来，它已被广泛接受为合成生物活性寡糖的快速且准确的方法。本综述试图聚焦于固相合成寡糖的各种方法及其应用。
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