Lellouche François, Taillé Solenne, Lefrançois Frédéric, Deye Nicolas, Maggiore Salvatore Maurizio, Jouvet Philippe, Ricard Jean-Damien, Fumagalli Bruno, Brochard Laurent
Service de Soins Intensifs de Chirurgie Cardiaque, Centre de Recherche Hôpital Laval, Université Laval, Québec City, QC, Canada.
Service de Réanimation Médicale, Assistance Publique-Hôpitaux de Paris, Centre Hospitalier Albert Chenevier-Henri-Mondor, Créteil, France.
Chest. 2009 Feb;135(2):276-286. doi: 10.1378/chest.08-0679.
Heat and moisture exchangers (HMEs) are increasingly used in the ICU for gas conditioning during mechanical ventilation. Independent assessments of the humidification performance of HMEs are scarce. The aim of the present study was thus to assess the humidification performance of a large number of adult HMEs.
We assessed 48 devices using a bench test apparatus that simulated real-life physiologic ventilation conditions. Thirty-two devices were described by the manufacturers as HMEs, and 16 were described as antibacterial filters. The test apparatus provided expiratory gases with an absolute humidity (AH) of 35 mg H(2)O/L. The AH of inspired gases was measured after steady state using the psychrometric method. We performed three hygrometric measurements for each device, measured their resistance, and compared our results with the manufacturer data.
Of the 32 HMEs tested, only 37.5% performed well (>or= 30 mg H(2)O/L), while 25% performed poorly (< 25 mg H(2)O/L). The mean difference (+/- SD) between our measurements and the manufacturer data was 3.0 +/- 2.7 mg H(2)O/L for devices described as HMEs (maximum, 8.9 mg H(2)O/L) [p = 0.0001], while the mean difference for 36% of the HMEs was > 4 mg H(2)O/L. The mean difference for the antibacterial filters was 0.2 +/- 1.4 mg H(2)O/L. The mean resistance of all the tested devices was 2.17 +/- 0.70 cm H(2)O/L/s.
Several HMEs performed poorly and should not be used as HMEs. The values determined by independent assessments may be lower than the manufacturer data. Describing a device as an HME does not guarantee that it provides adequate humidification. The performance of HMEs must be verified by independent assessment.
热湿交换器(HMEs)在重症监护病房(ICU)中越来越多地用于机械通气期间的气体调节。对HMEs加湿性能的独立评估很少。因此,本研究的目的是评估大量成人HMEs的加湿性能。
我们使用模拟实际生理通气条件的试验台装置评估了48种设备。制造商将32种设备描述为HMEs,16种描述为抗菌过滤器。试验台装置提供绝对湿度(AH)为35 mg H₂O/L的呼气气体。使用湿度测定法在稳态后测量吸气气体的AH。我们对每个设备进行了三次湿度测量,测量其阻力,并将我们的结果与制造商数据进行比较。
在测试的32种HMEs中,只有37.5%表现良好(≥30 mg H₂O/L),而25%表现不佳(<25 mg H₂O/L)。对于描述为HMEs的设备,我们的测量值与制造商数据之间的平均差异(±标准差)为3.0±2.7 mg H₂O/L(最大值为8.9 mg H₂O/L)[p = 0.0001],而36%的HMEs的平均差异>4 mg H₂O/L。抗菌过滤器的平均差异为0.2±1.4 mg H₂O/L。所有测试设备的平均阻力为2.17±0.70 cm H₂O/L/s。
几种HMEs表现不佳,不应用作HMEs。独立评估确定的值可能低于制造商数据。将一种设备描述为HME并不能保证它能提供足够的加湿。HMEs的性能必须通过独立评估来验证。