Thust R, Warzok R
Zentralbl Allg Pathol. 1977;121(1-2):82-6.
After transplacental application (30 mg/kg i.p., 3 days until 6 hours a. p.), diethylnitrosamine induces a high rate (76.2 per cent) of bronchiolar tumours in the lung of the Dzungarian hamster. These tumours were classified as papillary or tubulous adenomas and carcinomas. Furthermore, eome tumours were observed in other organs. The problem of organotropism of diethylnitrosamine, especially among different hamster hamster species, is discussed.
经胎盘给药(腹腔注射30毫克/千克,连续3天,直至下午6小时)后,二乙基亚硝胺可在准噶尔仓鼠肺中诱发高比例(76.2%)的细支气管肿瘤。这些肿瘤被分类为乳头状或管状腺瘤及癌。此外,在其他器官中也观察到了一些肿瘤。文中讨论了二乙基亚硝胺的器官嗜性问题,特别是在不同仓鼠物种之间。