Jacobs Joshua J, Urban Robert M, Hallab Nadim J, Skipor Anastasia K, Fischer Alfons, Wimmer Markus A
Department of Orthopaedic Surgery, Rush University Medical Center, Suite 1063, 1725 West Harrison Street, Chicago, IL 60612, USA.
J Am Acad Orthop Surg. 2009 Feb;17(2):69-76. doi: 10.5435/00124635-200902000-00003.
Metal-on-metal bearing couples remain a popular option in total hip arthroplasty and are the only currently available option for surface replacement arthroplasty. In general, the intermediate-term clinical performance of metal-on-metal bearings has been favorable. There are, however, lingering concerns about the biologic consequences of metal release from these bearings in terms of both local tissue effects, including delayed-type hypersensitivity reactions in a subset of patients, and potential systemic effects as a consequence of chronic elevations in serum cobalt and chromium content. Advances in the understanding of the operant wear mechanisms in these bearings provide strategies for reducing the burden of metal released into the periprosthetic milieu, which in turn will mitigate the concerns about the biologic response to the metal debris. Continued surveillance of patients with these bearings is warranted to determine whether metal-on-metal bearing couples provide a long-term survivorship advantage over other bearing couple options and to evaluate whether chronic elevations in the body burden of cobalt and chromium is well tolerated over the long term.
金属对金属轴承组合在全髋关节置换术中仍然是一种常用选择,并且是目前表面置换关节成形术唯一可用的选择。总体而言,金属对金属轴承的中期临床性能良好。然而,对于这些轴承释放金属所产生的生物学后果,无论是局部组织影响(包括一部分患者出现的迟发型超敏反应),还是血清钴和铬含量长期升高导致的潜在全身影响,人们一直心存担忧。对这些轴承中主要磨损机制认识的进展提供了减少释放到假体周围环境中金属负担的策略,这反过来将减轻对金属碎屑生物学反应的担忧。对使用这些轴承的患者进行持续监测是必要的,以确定金属对金属轴承组合是否比其他轴承组合选项具有长期生存优势,并评估长期来看钴和铬身体负担的长期升高是否能被良好耐受。