心脏移植

Heart transplantation.

作者信息

Yun J J, Gonzalez-Stawinski G

机构信息

Department of Cardiothoracic Surgery, Cleveland Clinic Foundation, Cleveland, OH, USA.

出版信息

Minerva Chir. 2009 Feb;64(1):23-35.

PMID:19202533

Abstract

Over the past 40 years, heart transplantation has become a routine treatment for end-stage heart failure. Over 3000 heart transplants are performed annually. Despite improvements in short-term outcomes, long-term survival remains limited. Current efforts remain directed at alleviating the shortage of donor organs, developing effective treatments for chronic rejection, and improving mechanical circulatory support for heart failure.

摘要

在过去40年里，心脏移植已成为终末期心力衰竭的常规治疗方法。每年进行超过3000例心脏移植手术。尽管短期疗效有所改善，但长期生存率仍然有限。目前的努力仍集中在缓解供体器官短缺、开发慢性排斥反应的有效治疗方法以及改善心力衰竭的机械循环支持方面。