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斐济的急性风湿热和风湿性心脏病:2005 - 2007年前瞻性监测

Acute rheumatic fever and rheumatic heart disease in Fiji: prospective surveillance, 2005-2007.

作者信息

Steer Andrew C, Kado Joseph, Jenney Adam W J, Batzloff Michael, Waqatakirewa Lepani, Mulholland E Kim, Carapetis Jonathan R

机构信息

Centre for International Child Health, University of Melbourne, Melbourne, VIC.

出版信息

Med J Aust. 2009 Feb 2;190(3):133-5. doi: 10.5694/j.1326-5377.2009.tb02312.x.

Abstract

OBJECTIVES

To determine the incidence and clinical features of acute rheumatic fever (ARF) in Fiji, and the clinical features of patients presenting to hospital in Fiji with rheumatic heart disease (RHD).

DESIGN AND SETTING

A prospective surveillance study at the Colonial War Memorial Hospital in Suva over a 23-month period from December 2005 to November 2007.

MAIN OUTCOME MEASURES

Incidence of ARF; clinical features of ARF and RHD.

RESULTS

The average annualised incidence of definite cases of ARF in children aged 5-15 years was 15.2 per 100,000 (95% CI, 9.0-22.6). The clinical features of ARF were similar to those in classic descriptions. Carditis was very common, occurring in 79% of cases. There were 103 admissions for RHD in which detailed information was collected, with the most common reason for admission being cardiac failure (51%). The median age at admission with RHD was 26.8 years, and there were 10 deaths of patients with RHD (case fatality rate, 9.7%).

CONCLUSIONS

Although apparently declining in incidence since the middle of the 20th century, ARF remains a significant health problem in Fiji. RHD affects young people, leading to premature morbidity and mortality. There is an urgent need for effective control of ARF and RHD in Fiji.

摘要

目的

确定斐济急性风湿热(ARF)的发病率和临床特征,以及斐济因风湿性心脏病(RHD)住院患者的临床特征。

设计与背景

2005年12月至2007年11月在苏瓦的殖民地战争纪念医院进行的一项前瞻性监测研究。

主要观察指标

ARF的发病率;ARF和RHD的临床特征。

结果

5至15岁儿童中确诊ARF病例的年均发病率为每10万人15.2例(95%可信区间,9.0 - 22.6)。ARF的临床特征与经典描述相似。心脏炎非常常见,79%的病例出现。收集了103例RHD住院患者的详细信息,最常见的住院原因是心力衰竭(51%)。RHD患者的入院中位年龄为26.8岁,有10例RHD患者死亡(病死率为9.7%)。

结论

尽管自20世纪中叶以来ARF发病率明显下降,但在斐济它仍然是一个重大的健康问题。RHD影响年轻人,导致过早发病和死亡。斐济迫切需要有效控制ARF和RHD。

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