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急性肺栓塞后早期医院再入院的预测因素。

Predictors of early hospital readmission after acute pulmonary embolism.

作者信息

Aujesky Drahomir, Mor Maria K, Geng Ming, Stone Roslyn A, Fine Michael J, Ibrahim Said A

机构信息

Service de Médecine Interne, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.

出版信息

Arch Intern Med. 2009 Feb 9;169(3):287-93. doi: 10.1001/archinternmed.2008.546.

Abstract

BACKGROUND

Risk factors for early mortality after pulmonary embolism (PE) are widely known. However, it is uncertain which factors are associated with early readmission after PE. We sought to identify predictors of readmission after an admission for PE.

METHODS

We studied 14 426 patient discharges with a primary diagnosis of PE from 186 acute care hospitals in Pennsylvania from January 1, 2000, to November 30, 2002. The outcome was readmission within 30 days of presentation for PE. We used a discrete proportional odds model to study the association between time to readmission and patient factors (age, sex, race, insurance, discharge status, and severity of illness), thrombolysis, and hospital characteristics (region, teaching status, and number of beds).

RESULTS

Overall, 2064 patient discharges (14.3%) resulted in a readmission within 30 days of presentation for PE. The most common reasons for readmission were venous thromboembolism (21.9%), cancer (10.8%), pneumonia (5.2%), and bleeding (5.0%). In multivariable analysis, African American race (odds ratio [OR], 1.19; 95% confidence interval [CI], 1.02-1.38), Medicaid insurance (OR, 1.54; 95% CI, 1.31-1.81), discharge home with supplemental care (OR, 1.40; 95% CI, 1.27-1.54), leaving the hospital against medical advice (OR, 2.84; 95% CI, 1.80-4.48), and severity of illness were independently associated with readmission; readmission also varied by hospital region.

CONCLUSIONS

Early readmission after PE is common. African American race, Medicaid insurance, severity of illness, discharge status, and hospital region are significantly associated with readmission. The high readmission rates for venous thromboembolism and bleeding suggest that readmission may be linked to suboptimal quality of care in the management of PE.

摘要

背景

肺栓塞(PE)后早期死亡的危险因素广为人知。然而,尚不确定哪些因素与PE后的早期再入院有关。我们试图确定PE入院后再入院的预测因素。

方法

我们研究了2000年1月1日至2002年11月30日期间宾夕法尼亚州186家急性护理医院中14426例以PE为主要诊断的患者出院情况。结局为PE就诊后30天内再入院。我们使用离散比例优势模型来研究再入院时间与患者因素(年龄、性别、种族、保险、出院状态和疾病严重程度)、溶栓治疗以及医院特征(地区、教学状态和床位数)之间的关联。

结果

总体而言,2064例患者出院(14.3%)在PE就诊后30天内再入院。再入院的最常见原因是静脉血栓栓塞(21.9%)、癌症(10.8%)、肺炎(5.2%)和出血(5.0%)。在多变量分析中,非裔美国人种族(优势比[OR],1.19;95%置信区间[CI],1.02 - 1.38)、医疗补助保险(OR,1.54;95% CI,1.31 - 1.81)、出院回家并接受补充护理(OR,1.40;95% CI,1.27 - 1.54)、违背医嘱出院(OR,2.84;95% CI,1.80 - 4.48)以及疾病严重程度与再入院独立相关;再入院情况也因医院地区而异。

结论

PE后的早期再入院很常见。非裔美国人种族、医疗补助保险、疾病严重程度、出院状态和医院地区与再入院显著相关。静脉血栓栓塞和出血的高再入院率表明,再入院可能与PE管理中护理质量欠佳有关。

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