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对分离性骨软骨炎松动体进行手术固定会导致愈合并长期维持膝关节功能吗?

Does operative fixation of an osteochondritis dissecans loose body result in healing and long-term maintenance of knee function?

作者信息

Magnussen Robert A, Carey James L, Spindler Kurt P

机构信息

Vanderbilt Orthopaedic Institute, Nashville, TN 37232-8774, USA.

出版信息

Am J Sports Med. 2009 Apr;37(4):754-9. doi: 10.1177/0363546508328119. Epub 2009 Feb 9.

Abstract

BACKGROUND

Osteochondritis dissecans (OCD) can progress to loose body formation, resulting in a grade IV defect. The decision to fix versus excise the loose body is controversial. Published operative fixation outcomes are small case series with short follow-up.

HYPOTHESIS

Operative fixation (ORIF) of the loose body into the grade IV defect will heal and approximate "normal" knee function at long-term follow-up.

STUDY DESIGN

Case series; Level of evidence, 4.

METHODS

Twelve patients were identified who underwent ORIF of a knee OCD loose body into the grade IV osteochondral defects ranging in size from 2.0 to 8.0 cm(2) (mean, 3.5 cm(2)). After 12 weeks, hardware was removed, and healing was assessed. Long-term outcomes were assessed with a Knee injury and Osteoarthritis Outcome Score (KOOS) and a Marx activity score.

RESULTS

Arthroscopy for screw removal revealed stable healing in 92% (11 of 12) of patients. No patients required subsequent surgery for a loose body. At an average of 9.2 years' follow-up (range, 3.8-15.8 years), 83% (10 of 12) of patients completed the KOOS. The KOOS subscale scores for pain (mean, 87.8; range, 67-100), other symptoms (mean, 81.8; range, 61-96), function in activities of daily living (mean, 93.1; range, 72-100), and sports and recreation function (mean, 74.0; range, 40-100) were not significantly lower than those of published age-matched controls. However the KOOS subscale score for knee-related quality of life (mean, 61.9; range, 31-88) was significantly lower (P = .003).

CONCLUSION

Operative fixation of grade IV OCD loose bodies results in stable fixation. At an average 9 years after surgery, patients did not have symptoms of osteoarthritis pain and had normal function in activities of daily life. However, patients reported significantly lower knee-related quality of life. Operative fixation of OCD loose bodies is a better alternative to lesion excision.

摘要

背景

剥脱性骨软骨炎(OCD)可发展为游离体形成,导致IV级缺损。决定固定还是切除游离体存在争议。已发表的手术固定结果是小样本病例系列且随访时间短。

假设

将游离体手术固定(切开复位内固定,ORIF)至IV级缺损处,在长期随访时将愈合并接近“正常”膝关节功能。

研究设计

病例系列;证据等级,4级。

方法

确定12例接受膝关节OCD游离体ORIF手术的患者,其IV级骨软骨缺损大小为2.0至8.0 cm²(平均3.5 cm²)。12周后取出内固定装置,并评估愈合情况。采用膝关节损伤和骨关节炎疗效评分(KOOS)及马克思活动评分评估长期结果。

结果

关节镜下取出螺钉显示92%(12例中的11例)患者愈合稳定。无患者因游离体需要再次手术。平均随访9.2年(范围3.8 - 15.8年),83%(12例中的10例)患者完成了KOOS评估。KOOS子量表中疼痛(平均87.8;范围67 - 100)、其他症状(平均81.8;范围61 - 96)、日常生活活动功能(平均93.1;范围72 - 100)和运动及娱乐功能(平均74.0;范围40 - 100)的评分均显著低于发表的年龄匹配对照组。然而,KOOS子量表中膝关节相关生活质量评分(平均61.9;范围31 - 88)显著更低(P = .003)。

结论

IV级OCD游离体的手术固定可实现稳定固定。术后平均9年,患者无骨关节炎疼痛症状,日常生活活动功能正常。然而,患者报告膝关节相关生活质量显著更低。OCD游离体的手术固定是病变切除的更好替代方法。

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