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自体骨软骨移植治疗膝关节剥脱性骨软骨炎:病例系列研究

Autogenous Osteochondral Grafting for Treatment of Knee Osteochondritis Dissecans: A Case Series Study.

作者信息

Keyhani Sohrab, Soleymanha Mehran, Verdonk René, Abbasian Mohammadreza

机构信息

Orthopedic Department Chair, Akhtar Orthopedic Training and Research Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Orthopaedic Research center, Department of Orthopaedic, Poursina Hospital and School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.

出版信息

Arch Bone Jt Surg. 2020 May;8(3):426-431. doi: 10.22038/abjs.2019.39026.2038.

DOI:10.22038/abjs.2019.39026.2038
PMID:32766403
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7358228/
Abstract

BACKGROUND

Although some surgical techniques have been described for the operative treatment of unstable Osteochondritis dissecans (OCD) of the knee, outcomes are variable and are not satisfying totally. The aim of the present study is to evaluate the outcomes of autogenous osteochondral grafting for OCD of the knee.

METHODS

In a case series study, from June 2014 to July 2015, 16 patients with stage II-IV OCD (International Cartilage Repair Society (ICRS)) of the femoral condyle were investigated. Surgical intervention considered in cases of stage III (4 cases) and IV (2 cases) and in stage II (10 cases) ones that were nonresponsive to conservative treatment. At the initial and final visits, the IKDC, Lysholm score and Tegner activity scale were evaluated.

RESULTS

The mean preoperative IKDC score (53.4) increased significantly following surgery (84.3) (). Based on the IKDC grading system, before the operation, the knee status was graded as nearly normal, abnormal, and severely abnormal in 4, 10, and 2 patients, respectively. At final post-surgical follow up, 15 normal and 1 abnormal knee were documented (). The mean Lysholm score increased from 44.3 per operatively to 86.3 ().Tegner activity score improved from 2.8±1 pre operatively to 5.6±2 ().

CONCLUSION

Surgical treatment of unstable OCD using autogenous osteochondral graft shows successful outcomes. In addition to reliable fixation, it can enhance healing and convert an uncontained lesion to contained one appropriate for autogenous osteochondral grafting with healthy cartilage.

摘要

背景

尽管已经描述了一些用于膝关节不稳定剥脱性骨软骨炎(OCD)手术治疗的外科技术,但结果各不相同,且总体上并不令人满意。本研究的目的是评估自体骨软骨移植治疗膝关节OCD的效果。

方法

在一项病例系列研究中,对2014年6月至2015年7月期间16例股骨髁II-IV期OCD(国际软骨修复协会(ICRS))患者进行了调查。对III期(4例)和IV期(2例)以及对保守治疗无反应的II期(10例)患者进行手术干预。在初次和末次随访时,评估IKDC、Lysholm评分和Tegner活动量表。

结果

术前IKDC平均评分(53.4)术后显著提高(84.3)()。根据IKDC分级系统,术前膝关节状态分级为接近正常、异常和严重异常的患者分别为4例、10例和2例。术后最终随访时,记录到15例膝关节正常,1例异常()。Lysholm平均评分从术前的44.3提高到86.3()。Tegner活动评分从术前的2.8±1提高到5.6±2()。

结论

使用自体骨软骨移植治疗不稳定OCD手术效果良好。除了可靠的固定外,它还可以促进愈合,并将非包容性病变转变为适合自体健康软骨骨软骨移植的包容性病变。

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本文引用的文献

1
Implant failure after biodegradable screw fixation in osteochondritis dissecans of the knee in skeletally immature patients.骨骼未成熟患者膝关节剥脱性骨软骨炎采用可生物降解螺钉固定后的植入物失败情况。
Arthroscopy. 2015 Mar;31(3):410-5. doi: 10.1016/j.arthro.2014.08.032. Epub 2014 Nov 6.
2
Evidence-based status of osteochondral cylinder transfer techniques: a systematic review of level I and II studies.基于证据的骨软骨柱移植技术现状:I 级和 II 级研究的系统评价。
Arthroscopy. 2014 Apr;30(4):497-505. doi: 10.1016/j.arthro.2013.12.023.
3
Clinical outcome of internal fixation of unstable juvenile osteochondritis dissecans lesions of the knee.青少年膝关节不稳定剥脱性骨软骨炎损伤内固定的临床结果
Orthopedics. 2013 Nov;36(11):e1444-9. doi: 10.3928/01477447-20131021-30.
4
Osteochondral autograft transplantation for juvenile osteochondritis dissecans of the knee: a series of twelve cases.膝关节骨软骨病软骨移植治疗青少年剥脱性骨软骨炎:十二例系列研究。
Int Orthop. 2012 Nov;36(11):2243-8. doi: 10.1007/s00264-012-1648-9. Epub 2012 Sep 7.
5
Does extracorporeal shock wave therapy enhance healing of osteochondritis dissecans of the rabbit knee?: a pilot study.体外冲击波疗法是否能促进兔膝剥脱性骨软骨炎的愈合?:一项初步研究。
Clin Orthop Relat Res. 2013 Apr;471(4):1159-65. doi: 10.1007/s11999-012-2410-8.
6
Drilling juvenile osteochondritis dissecans: retro- or transarticular?青少年剥脱性骨软骨炎钻孔:经关节内还是关节外?
Clin Orthop Relat Res. 2013 Apr;471(4):1144-51. doi: 10.1007/s11999-011-2237-8.
7
Juvenile osteochondritis of femoral condyles: treatment with transchondral drilling. Analysis of 40 cases.青少年股骨髁骨软骨炎:经软骨钻孔治疗。40例分析。
J Child Orthop. 2010 Feb;4(1):39-44. doi: 10.1007/s11832-009-0225-2. Epub 2009 Dec 18.
8
Treatment of osteochondritis dissecans of the femoral condyle with autologous bone grafts and matrix-supported autologous chondrocytes.自体骨移植和基质支持自体软骨细胞治疗股骨髁剥脱性骨软骨炎。
Int Orthop. 2010 Aug;34(6):819-25. doi: 10.1007/s00264-009-0841-y. Epub 2009 Jul 22.
9
Does operative fixation of an osteochondritis dissecans loose body result in healing and long-term maintenance of knee function?对分离性骨软骨炎松动体进行手术固定会导致愈合并长期维持膝关节功能吗?
Am J Sports Med. 2009 Apr;37(4):754-9. doi: 10.1177/0363546508328119. Epub 2009 Feb 9.
10
Fixation of unstable osteochondritis dissecans lesions of the knee using arthroscopic autogenous osteochondral grafting (mosaicplasty).使用关节镜下自体骨软骨移植术(马赛克成形术)固定膝关节不稳定的剥脱性骨软骨炎病变。
Arthroscopy. 2007 Aug;23(8):845-51. doi: 10.1016/j.arthro.2007.02.017.