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膝关节成人剥脱性骨软骨炎的手术治疗中期结果。

Midterm results of surgical treatment for adult osteochondritis dissecans of the knee.

机构信息

Rush University Medical Center, 1725 West Harrison Street, Chicago, IL 60612, USA.

出版信息

Am J Sports Med. 2009 Nov;37 Suppl 1:125S-30S. doi: 10.1177/0363546509350833. Epub 2009 Oct 27.

Abstract

BACKGROUND

Determination of appropriate treatment options for adult osteochondritis dissecans is difficult, as most published papers on surgical osteochondritis dissecans treatment report outcomes in a population consisting of both adult and juvenile patients.

PURPOSE

This study examines the outcomes of surgical procedures in patients with adult osteochondritis dissecans.

STUDY DESIGN

Case series; Level of evidence, 4.

METHODS

The cohort included 46 adult patients (48 knees) with adult osteochondritis dissecans of the knee who had undergone surgical treatment (debridement, drilling, loose-body removal, arthroscopic reduction and internal fixation, microfracture, osteochondral allograft, or autologous chondrocyte implantation). The average patient age was 34 +/- 9.5 years (range, 20-49) and patients were followed for 4.0 +/- 1.8 years. The mean defect size was 4.5 +/- 2.7 cm(2). Outcomes were assessed via clinical assessment and established outcome scales, including the Lysholm, International Knee Documentation Committee (IKDC), Knee Injury and Osteoarthritis Outcome Score (KOOS), Tegner, Cincinnati, and Short Form-12.

RESULTS

Statistically significant improvement (P < .05) was noted in all outcome scales, including Noyes, Tegner, Lysholm, IKDC, KOOS (subdivided into 5 categories including Pain, Symptoms, Activities of Daily Living, Sport, and Quality of Life), Short Form-12 Physical, and Short Form-12 Mental. Seven knees (14%) had clinical failure of the initial treatment and underwent a revision procedure at a mean follow-up of 14 months. Patients treated with arthroscopic reduction and internal fixation and loose-body removal demonstrated a statistically higher postoperative percentage score increase for the KOOS Sport (P = .008) and KOOS Quality of Life (P = .03) categories than those treated with an osteochondral allograft.

CONCLUSION

Patients with adult osteochondritis dissecans of the knee, treated with surgical cartilage procedures, show durable function and symptomatic improvement at a mean 4.0 years of follow-up. Patients treated with arthroscopic reduction and internal fixation and loose-body removal demonstrated a greater improvement in outcome scores than those treated with osteochondral allograft.

摘要

背景

成人剥脱性骨软骨炎的治疗方案选择较为困难,因为大多数关于手术治疗剥脱性骨软骨炎的研究报告中,患者人群包括成人和青少年。

目的

本研究旨在探讨成人剥脱性骨软骨炎的手术治疗效果。

研究设计

病例系列研究;证据等级,4 级。

方法

本研究纳入了 46 例(48 膝)接受手术治疗的成人剥脱性骨软骨炎患者,手术方法包括清创术、钻孔术、游离体去除术、关节镜下复位内固定术、微骨折术、骨软骨同种异体移植术或自体软骨细胞移植术。患者平均年龄为 34±9.5 岁(范围,20-49 岁),随访时间为 4.0±1.8 年。平均缺损面积为 4.5±2.7cm²。通过临床评估和既定的评估量表(包括 Lysholm 评分、国际膝关节文献委员会(IKDC)评分、膝关节损伤和骨关节炎评分(KOOS)、Tegner 评分、Cincinnati 评分和 12 项简明健康量表)评估患者的预后。

结果

所有评估量表(包括 Noyes 评分、Tegner 评分、Lysholm 评分、IKDC 评分、KOOS 评分[分为疼痛、症状、日常生活活动、运动和生活质量 5 个亚类]、12 项简明健康量表躯体功能评分和 12 项简明健康量表精神健康评分)的评分均有统计学意义上的显著改善(P<0.05)。7 例(14%)患者初始治疗失败,在平均 14 个月的随访时行翻修手术。接受关节镜下复位内固定术和游离体去除术治疗的患者,KOOS 运动亚类(P=0.008)和 KOOS 生活质量亚类(P=0.03)的术后百分比评分增加显著高于接受骨软骨同种异体移植术治疗的患者。

结论

接受关节镜下复位内固定术和游离体去除术等关节内手术治疗的成人剥脱性骨软骨炎患者,在平均 4.0 年的随访中,膝关节功能和症状均有持久改善。与骨软骨同种异体移植术相比,接受关节镜下复位内固定术和游离体去除术治疗的患者,其术后评分改善更显著。

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