Gómez-León Mandujano Amir, Amezcua-Guerra Luis Manuel
Departamento de Cardiologia Geriatrica, Instituto Nacional de Cardiologia Ignacio Chavez, México.
Arch Cardiol Mex. 2008 Oct-Dec;78(4):421-30.
Pericarditis is the most common cardiac manifestation in systemic lupus erythematosus (SLE) patients, although lesions of valves, myocardium and coronary arteries may also occur. In the past, cardiac abnormalities were severe and life threatening. Nowadays, cardiac manifestations are often mild and asymptomatic. However, they can be easily recognized by echocardiography and other novel tests. Vascular occlusion, including coronary vessels, may develop due to vasculitis, premature atherosclerosis or antiphospholipid antibodies. Premature atherosclerosis is the most frequent cause of coronary artery disease in SLE patients. Efforts should be made to control traditional risk factors as well as all other factors that are intrinsic to SLE, which could contribute to atherosclerotic plaque development.
心包炎是系统性红斑狼疮(SLE)患者最常见的心脏表现,尽管瓣膜、心肌和冠状动脉也可能出现病变。过去,心脏异常严重且危及生命。如今,心脏表现通常较轻且无症状。然而,通过超声心动图和其他新型检查很容易识别它们。血管闭塞,包括冠状动脉闭塞,可能由于血管炎、过早动脉粥样硬化或抗磷脂抗体而发生。过早动脉粥样硬化是SLE患者冠状动脉疾病最常见的原因。应努力控制传统危险因素以及SLE固有的所有其他可能导致动脉粥样硬化斑块形成的因素。