Mukherjee Aparna, Lodha Rakesh, Kabra S K
Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.
Indian J Pediatr. 2009 Apr;76(4):430-2. doi: 10.1007/s12098-009-0002-8. Epub 2009 Feb 10.
Idiopathic CD4+ T lymphocytopenia (ICL) is an unusual immune defect in which there is an unexplained deficit of CD4+ T cells, leading to serious opportunistic infections. In view of the rarity of this clinical entity, we report two cases of ICL who presented with low CD4+ count or percentage and various opportunistic infections like candida, cytomegalovirus, Mycobacterium tuberculosis.
特发性CD4⁺T淋巴细胞减少症(ICL)是一种罕见的免疫缺陷病,其特征为CD4⁺T细胞数量不明原因减少,可导致严重的机会性感染。鉴于该临床病症较为罕见,我们报告两例ICL患者,其CD4⁺细胞计数或百分比偏低,并伴有念珠菌、巨细胞病毒、结核分枝杆菌等多种机会性感染。