Petersen E J, Rozenberg-Arska M, Dekker A W, Clevers H C, Verdonck L F
Department of Haematology, University Hospital Utrecht, The Netherlands.
Bone Marrow Transplant. 1996 Oct;18(4):813-5.
CD4+ T-lymphocytopenia in the absence of HIV infection is a heterogeneous disorder of unknown cause. Here we report a patient with idiopathic CD4+ T-lymphocytopenia, presenting with an opportunistic Rhodococcus equi infection. When aplastic anemia developed subsequently, allogeneic bone marrow transplantation was performed. Complete restoration of immune function was observed. We conclude that allogeneic bone marrow transplantation presents a potentially curative therapy for CD4+ T-lymphocytopenia.
无HIV感染情况下的CD4+ T淋巴细胞减少是一种病因不明的异质性疾病。在此，我们报告一例特发性CD4+ T淋巴细胞减少患者，该患者出现机会性马红球菌感染。随后发生再生障碍性贫血时，进行了异基因骨髓移植。观察到免疫功能完全恢复。我们得出结论，异基因骨髓移植是CD4+ T淋巴细胞减少的一种潜在治愈性疗法。
