Orhan Zafer, Oktas Birhan, Yildirim Umran
Department of Orthopedics and Traumatology, Duzce Medical Faculty, Duzce University, Duzce, Turkey.
Knee Surg Sports Traumatol Arthrosc. 2009 May;17(5):518-20. doi: 10.1007/s00167-009-0720-5. Epub 2009 Feb 10.
Pigmented villonodular synovitis (PVS) is a benign proliferative disorder of unknown origin that affects synovial joints, most commonly the knee. The joint knee can be affected by localized or diffuse form. Diffuse PVS, the aggressive form of the disease is much more problematic, especially when it extends extra-articularly, and is associated with high recurrence rates. Although this disease is categorized as an inflammatory process rather than a neoplasm, it may be locally destructive and involve muscles, tendons, bone and skin. Neural involvement of the disease is rather rare, and only limited knowledge about neuropathy due to PVS we have yet. The presentation of the disease in our patient is a peroneal neuropathy which is the first reported case in English language literature of PVS of the knee seen with extra-articular tissue involvement.
色素沉着绒毛结节性滑膜炎（PVS）是一种起源不明的良性增殖性疾病，可累及滑膜关节，最常见于膝关节。膝关节可受到局限性或弥漫性形式的影响。弥漫性PVS是该疾病的侵袭性形式，问题要大得多，尤其是当它延伸至关节外时，且复发率很高。尽管这种疾病被归类为炎症过程而非肿瘤，但它可能具有局部破坏性，可累及肌肉、肌腱、骨骼和皮肤。该疾病累及神经相当罕见，目前我们对PVS所致神经病变的了解有限。我们患者的疾病表现为腓总神经病变，这是英文文献中首次报道的膝关节PVS伴关节外组织受累的病例。
