从羊腐蹄病中分离出的拟杆菌属和梭杆菌属对28种抗菌剂的体外敏感性比较

Comparative in vitro susceptibility of Bacteroides and Fusobacterium isolated from footrot in sheep to 28 antimicrobial agents.

作者信息

Píriz Durán S, Cuenca Valera R, Valle Manzano J, Vadillo Machota S

机构信息

Unidad de Microbiología e Inmunología, Facultad de Veterinaria, Universidad de Extremadura, Cáceres, Spain.

出版信息

J Vet Pharmacol Ther. 1991 Jun;14(2):185-92. doi: 10.1111/j.1365-2885.1991.tb00821.x.

DOI:10.1111/j.1365-2885.1991.tb00821.x

PMID:1920606

Abstract

The agar dilution method was used to determine the bacteriostatic activity of 28 antimicrobial agents against 141 strains to the genus Bacteroides and 29 strains from the genus Fusobacterium. All organisms were isolated from clinical cases of ovine footrot. The strains were isolated from 125 Merino sheep, over a period of 2 years, from January 1987 to December 1988. The three ureidopenicillins studied (azlocillin, mezlocillin and piperacillin) proved to be the most effective antimicrobial agents. Chloramphenicol, metronidazole and tinidazole effectively inhibited the growth of Bacteroides spp., while phosphomycin was active against Fusobacterium spp.

摘要

采用琼脂稀释法测定了28种抗菌剂对141株拟杆菌属菌株和29株梭杆菌属菌株的抑菌活性。所有菌株均从绵羊足腐病临床病例中分离得到。这些菌株是在1987年1月至1988年12月的两年时间里从125只美利奴绵羊中分离出来的。所研究的三种脲基青霉素（阿洛西林、美洛西林和哌拉西林）被证明是最有效的抗菌剂。氯霉素、甲硝唑和替硝唑能有效抑制拟杆菌属细菌的生长，而磷霉素对梭杆菌属细菌有活性。