Nam Ki Tae, Lee Yun Jung, Krauland Eric M, Kottmann Stephen T, Belcher Angela M
Department of Materials Science & Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
ACS Nano. 2008 Jul;2(7):1480-6. doi: 10.1021/nn800018n.
Herein we report the spontaneous reduction of silver ions into nanostructures by yeast surface-displayed glutamic acid (E(6)) and aspartic acid (D(6)) peptides. Light spectroscopy and electron microscopy reveal that silver ions are photoreduced in the presence of the polycarboxylic acid-containing peptides and ambient light, with an increase in reduction capability of E(6) expressing yeast over D(6) yeast. The importance of tethering peptides to a biological scaffold was inferred by observing the reduced particle forming capacity of soluble peptides with respect to corresponding yeast-displayed peptides. This principle was further extended to the M13 virus for fabrication of crystalline silver nanowires. These insights into the spontaneous reduction of metal ions on biological scaffolds should help further the formation of novel nanomaterials in biological systems.
在此，我们报道了通过酵母表面展示的谷氨酸（E(6)）和天冬氨酸（D(6)）肽将银离子自发还原为纳米结构。光谱学和电子显微镜显示，在含多元羧酸肽和环境光存在下，银离子被光还原，表达E(6)的酵母比表达D(6)的酵母还原能力更强。通过观察可溶性肽相对于相应酵母展示肽形成还原颗粒的能力，推断出将肽连接到生物支架上的重要性。这一原理进一步扩展到用于制造结晶银纳米线的M13病毒。这些关于生物支架上金属离子自发还原的见解应有助于在生物系统中进一步形成新型纳米材料。
