Anderson C A, Curzon M E J, Van Loveren C, Tatsi C, Duggal M S
Department of Paediatric Dentistry, Child Dental Health, Leeds Dental Institute, Leeds, UK.
Obes Rev. 2009 Mar;10 Suppl 1:41-54. doi: 10.1111/j.1467-789X.2008.00564.x.
The aim of this study was to conduct a review of the literature to assess the relationship between quantity and pattern of sucrose use and dental caries. Using hand and electronic methods (MEDLINE, EMBASE) the literature was searched for epidemiological papers concerning any relationship of sugars and dental caries published since 1856. Superficial hand searching was carried out between 1856 and 1940, detailed hand searching 1940-1966 and electronic 1966-2007. Selection criteria were set based on, but not confined to, Cochran style standards. Investigations were categorized as A, fulfilling all criteria; B1, relevant fulfilling 19 of 23 criteria; B2, relevant but fulfilling only between 12 and 18 of the selection criteria; and C, all other papers. There were 95 papers meeting most (more than 12) or all of the selected criteria. Only 1 paper was graded A; 31 as B1. There were in addition some 65 as B2 and all the rest as C, which were discarded. There were a wide variety of study designs and those graded A or B1 comprised 23 ecological cross-sectional, 7 cohort and 2 case control studies. Summary results showed that 6 papers found a positive, significant relationship of sugar quantity to dental caries, 19 of 31 studies reported a significant relationship of sugar frequency of use to dental caries. The balance of studies does not demonstrate a relationship between sugar quantity, but a moderately significant relationship of sugar frequency to dental caries.
本研究旨在对文献进行综述，以评估蔗糖摄入量及摄入模式与龋齿之间的关系。通过手工检索及电子检索方法（MEDLINE、EMBASE），查找自1856年以来发表的有关糖类与龋齿关系的流行病学论文。1856年至1940年进行了粗略的手工检索，1940年至1966年进行了详细的手工检索，1966年至2007年进行了电子检索。选择标准基于但不限于Cochran标准设定。研究被分为A类，满足所有标准；B1类，相关且满足23项标准中的19项；B2类，相关但仅满足12至18项选择标准；C类，其他所有论文。共有95篇论文符合大部分（超过12项）或所有选定标准。只有1篇论文被评为A类；31篇为B1类。此外，约有65篇为B2类，其余均为C类，后者被剔除。研究设计多种多样，评为A类或B1类的研究包括23项生态横断面研究、7项队列研究和2项病例对照研究。总结结果显示，6篇论文发现糖摄入量与龋齿呈正相关且具有显著关系，31项研究中有19项报告糖摄入频率与龋齿存在显著关系。研究结果的整体情况并未表明糖摄入量与龋齿之间存在关系，但糖摄入频率与龋齿之间存在中度显著关系。
