Yano F, Sherif A E, Turaga K, Stadlhuber R J, Tsuboi K, Ramaswamy S, Mittal S K
Department of Surgery, Creighton University Medical Center, Omaha, Nebraska 68131-2197, USA.
Dis Esophagus. 2009;22(2):177-84. doi: 10.1111/j.1442-2050.2008.00895.x. Epub 2008 Dec 22.
A subset of patients does not report improvement of symptoms or satisfaction after antireflux surgery. The aim of this study is to assess the effect of pre-existing depression as a factor in patient satisfaction and gastrointestinal quality of life index (GIQLI) outcomes after antireflux surgery. Patients undergoing antireflux surgery who had filled a preoperative quality of life score and had more than 1 year follow-up were included in this study. Based on available history and self-reported medication use, patients were divided in two groups: with depression (group A) and without depression (group B). Fifty-four patients with completed preoperative GIQLI questionnaire were contacted for this study; 32 (59%) patients completed the postoperative questionnaire. Seven patients (22%) had psychological disorder (group A) in the form of depression The GIQLI in groups A and B increased significantly from 64.4 +/- 17.3 and 89.6 +/- 18.6 to 88.6 +/- 23.7 (P < 0.001) and 102.2 +/- 18.6 (P = 0.02), respectively, after the surgery. There was significant improvement in the quality of life in patients after antireflux surgery based on the GIQLI assessment. This improvement was also reported in patients with history of depression.
一部分患者在抗反流手术后并未报告症状改善或满意度提高。本研究的目的是评估术前存在的抑郁作为抗反流手术后患者满意度和胃肠道生活质量指数（GIQLI）结果的一个因素的影响。本研究纳入了接受抗反流手术且术前填写了生活质量评分并进行了超过1年随访的患者。根据现有的病史和自我报告的用药情况，患者被分为两组：有抑郁组（A组）和无抑郁组（B组）。本研究联系了54名完成术前GIQLI问卷的患者；32名（59%）患者完成了术后问卷。7名患者（22%）患有以抑郁形式存在的心理障碍（A组）。手术后，A组和B组的GIQLI分别从64.4±17.3和89.6±18.6显著提高到88.6±23.7（P<0.001）和102.2±18.6（P=0.02）。根据GIQLI评估，抗反流手术后患者的生活质量有显著改善。有抑郁病史的患者也报告了这种改善。
