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日本人群中B淋巴细胞和T淋巴细胞衰减器基因与1型糖尿病或系统性红斑狼疮的关联研究。

Association study between B- and T-lymphocyte attenuator gene and type 1 diabetes mellitus or systemic lupus erythematosus in the Japanese population.

作者信息

Inuo M, Ihara K, Matsuo T, Kohno H, Hara T

机构信息

Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Higashiku, Fukuoka, Japan.

出版信息

Int J Immunogenet. 2009 Feb;36(1):65-8. doi: 10.1111/j.1744-313X.2008.00809.x.

DOI:10.1111/j.1744-313X.2008.00809.x
PMID:19207938
Abstract

This study is to elucidate whether the B- and T-lymphocyte attenuator (BTLA) gene is a new susceptibility gene for the development of type 1 diabetes (T1D) and systemic lupus erythematosus (SLE). As a result, this study did not find any genetic contribution of the BTLA gene to the development of T1D and SLE in Japanese population.

摘要

本研究旨在阐明B和T淋巴细胞衰减器（BTLA）基因是否是1型糖尿病（T1D）和系统性红斑狼疮（SLE）发病的新的易感基因。结果，本研究未发现BTLA基因对日本人群中T1D和SLE的发病有任何遗传贡献。

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