Inuo M, Ihara K, Matsuo T, Kohno H, Hara T
Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Higashiku, Fukuoka, Japan.
Int J Immunogenet. 2009 Feb;36(1):65-8. doi: 10.1111/j.1744-313X.2008.00809.x.
This study is to elucidate whether the B- and T-lymphocyte attenuator (BTLA) gene is a new susceptibility gene for the development of type 1 diabetes (T1D) and systemic lupus erythematosus (SLE). As a result, this study did not find any genetic contribution of the BTLA gene to the development of T1D and SLE in Japanese population.
本研究旨在阐明B和T淋巴细胞衰减器(BTLA)基因是否是1型糖尿病(T1D)和系统性红斑狼疮(SLE)发病的新的易感基因。结果,本研究未发现BTLA基因对日本人群中T1D和SLE的发病有任何遗传贡献。