D'Angelo Salvatore, Mennillo Gianna Angela, Cutro Maria Stefania, Leccese Pietro, Nigro Angelo, Padula Angela, Olivieri Ignazio
Rheumatology Department of Lucania, Ospedale San Carlo, Contrada Macchia Romana, 85100 Potenza, Italy.
J Rheumatol. 2009 Feb;36(2):368-70. doi: 10.3899/jrheum.080596. Epub 2009 Feb 4.
OBJECTIVE: To determine the sensitivity of the CASPAR criteria in patients with early psoriatic arthritis (PsA). METHODS: Consecutive patients with a clinical diagnosis of PsA and a disease duration < 12 months were enrolled for study. The proportion of patients meeting the criteria (i.e., the sensitivity) was determined. RESULTS: Forty-four patients with early PsA (23 women, 21 men; mean age 51 yrs, range 16-90) were enrolled. Mean disease duration (+/- SD) was 15.8 +/- 14.3 weeks (range 0.1-50.9 wks). Thirty-four patients satisfied the criteria at the first visit (sensitivity 77.3%). Most patients met the skin and laboratory criterion, i.e., they were rheumatoid factor-negative, while only 2 satisfied the radiologic criterion. CONCLUSION: Our findings suggest a less satisfactory performance of the CASPAR criteria when applied in early PsA. Lower sensitivity could mainly depend on the small proportion of patients fulfilling the radiologic criterion.
目的：确定CASPAR标准对早期银屑病关节炎（PsA）患者的敏感性。 方法：纳入临床诊断为PsA且病程<12个月的连续患者进行研究。确定符合标准的患者比例（即敏感性）。 结果：纳入44例早期PsA患者（23例女性，21例男性；平均年龄51岁，范围16 - 90岁）。平均病程（±标准差）为15.8±14.3周（范围0.1 - 50.9周）。34例患者首次就诊时符合标准（敏感性77.3%）。大多数患者符合皮肤和实验室标准，即类风湿因子阴性，而只有2例符合放射学标准。 结论：我们的研究结果表明，CASPAR标准应用于早期PsA时表现不太理想。较低的敏感性可能主要取决于符合放射学标准的患者比例较小。
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