Semiz Serap, Kurt Funda, Kurt Devrim Tanil, Zencir Mehmet, Sevinç Ozgür
Division of Pediatric Endocrinology, Department of Pediatrics, Pamukkale University Faculty of Medicine, Denizli, Turkey.
J Pediatr Endocrinol Metab. 2008 Oct;21(10):951-61. doi: 10.1515/jpem.2008.21.10.951.
To investigate the pubertal development of Turkish school children, to look for possible secular trends in pubertal development.
1,562 girls and 1,749 boys (aged 6-16.5 years) from urban and rural schools were studied. Weight and height were measured and body mass index was calculated. Pubertal stages were assessed according to Tanner. Testicular volume was determined using an orchidometer. Menarcheal age was recorded.
In girls, mean ages at breast stage (B) were 7.74 +/- 1.08 years for B1, 10.16 +/- 0.97 for B2, 11.72 +/- 1.29 for B3, 12.97 +/- 1.17 for B4, and 13.66 +/- 0.89 for B5. Mean ages at pubic hair stage (PH) were 8.72 +/- 1.50 years for PH1, 10.57 +/- 1.39 for PH2, 12.12 +/- 1.10 for PH3, 13.10 +/- 1.04 for PH4, and 13.87 +/- 0.83 for PH5. Mean age at menarche was 12.41 years. Menarcheal age was earlier in overweight and obese children compared with that in normal children. In boys, mean ages at each maturity stage according to testis volume (G) were 8.70 +/- 1.38 years for G1, 11.76 +/- 1.28 for G2, 12.81 +/- 1.0 for G3, 13.17 +/- 0.87 for G4, and 13.87 +/- 0.98 for G5. Mean ages at PH in boys were 9.39 +/- 1.81 years for PH1, 12.02 +/- 1.33 for PH2, 13.05 +/- 0.88 for PH3, 13.42 +/- 0.87 for PH4, and 14.02 +/- 0.92 for PH5.
The current study provides an up-to-date reference of normal sexual maturation of Turkish children. While the mean age at onset of puberty in boys was comparable to that of other populations in the world, girls were found to start pubertal development earlier than in other populations.
研究土耳其学龄儿童的青春期发育情况，探寻青春期发育中可能存在的长期趋势。
对来自城乡学校的1562名女孩和1749名男孩（年龄在6至16.5岁之间）进行了研究。测量了体重和身高，并计算了体重指数。根据坦纳法评估青春期阶段。使用睾丸体积测量器测定睾丸体积。记录月经初潮年龄。
在女孩中，乳房发育阶段（B）的平均年龄分别为：B1期7.74±1.08岁，B2期10.16±0.97岁，B3期11.72±1.29岁，B4期12.97±1.17岁，B5期13.66±0.89岁。阴毛发育阶段（PH）的平均年龄分别为：PH1期8.72±1.50岁，PH2期10.57±1.39岁，PH3期12.12±1.10岁，PH4期13.10±1.04岁，PH5期13.87±0.83岁。月经初潮的平均年龄为12.41岁。超重和肥胖儿童的月经初潮年龄比正常儿童更早。在男孩中，根据睾丸体积划分的各成熟阶段的平均年龄分别为：G1期8.70±1.38岁，G2期11.76±1.28岁，G3期12.81±1.0岁，G4期13.17±0.87岁，G5期13.87±0.98岁。男孩阴毛发育阶段（PH）的平均年龄分别为：PH1期9.39±1.81岁，PH2期12.02±1.33岁，PH3期13.05±0.88岁,PH4期13.42±0.87岁，PH5期14.02±0.92岁。
本研究提供了土耳其儿童正常性成熟的最新参考数据。虽然男孩青春期开始的平均年龄与世界其他人群相当，但发现女孩青春期发育开始得比其他人群更早。
