Coignard-Biehler Hélène, Lanternier Fanny, de Montalembert Mariane, Mahlaoui Nizar, Suarez Felipe, Lecuit Marc, Lortholary Olivier
Université Paris-Descartes, Assistance publique-Hôpitaux de Paris, hôpital Necker-Enfants malades, Paris, France.
Rev Prat. 2008 Dec 31;58(20):2209-14.
Overwhelming post-splenectomy infection (OPSI) is a long-term risk in asplenic patients, which may be controlled by appropriate preventive measures. Specific guidelines have been developed to reduce its incidence. These guidelines include immunizations, antibioprophylaxis, and education. Immunizations against S. pneumoniae, N. meningitidis, Hamophilus influenzae, and influenza should be administered. Antibioprophylaxis during 2 to 5 years following splenectomy in children, and 2 years in adults is recommended. Furthermore, long-term education is mandatory. Application of preventing measures is effective and patient's education remains the cornerstone of prevention.
脾切除术后暴发性感染（OPSI）是脾切除患者面临的长期风险，可通过适当的预防措施加以控制。已制定了具体指南以降低其发生率。这些指南包括免疫接种、抗生素预防和教育。应接种针对肺炎链球菌、脑膜炎奈瑟菌、流感嗜血杆菌和流感的疫苗。建议儿童在脾切除术后2至5年、成人在术后2年进行抗生素预防。此外，长期教育是必要的。采取预防措施是有效的，而患者教育仍然是预防的基石。
