Zarzycka Beata, Pieczara Anna, Skowron-Kobos Jolanta, Krzemiński Zbigniew
Zakład Mikrobiologii Lekarskiej Uniwersytetu Medycznego w Lodzi.
Przegl Epidemiol. 2008;62(4):759-65.
Bartonella henselae is a cat scratch disease's etiological agent which is usually manifestated as regional lymphadenopathy. In differential diagnosis of lymphadenopathy infections about etiology B. henselae are rarely taken into consideration. Enlargement of lymph nodes observed in children more often than in adults are caused by bacterial, virus or parasitic factors. In this study immunoglobulines G class antibodies to B. henselae were determined among children with limphadenopathy. At 53 children with recognized lymphadenopathy IgG antibodies were determined by indirect immunofluoroscence method specific for B. henselae. Of the 53 subjects examined, positive results were got at 29 (55%) children. Of the 23 children with negative results of IgG antibodies in 9 children study was repeated. In 5 (56%) cases the increase of IgG antibodies were shown with relation to the first research. The cat scratch disease should be considered as a cause of lymphadenopathy at children because the frequency of occurance of antibodies IgG specific for B. henselae is high. In case of getting negative results, participation of B. henselae should not be out of question in limphadenopathy etiology at children and second determination should be repeted after 10-21 days since the first one.
汉赛巴尔通体是猫抓病的病原体，通常表现为局部淋巴结病。在淋巴结病感染的病因鉴别诊断中，很少考虑汉赛巴尔通体。儿童中观察到的淋巴结肿大比成人更常见，其由细菌、病毒或寄生虫因素引起。在本研究中，对患有淋巴结病的儿童检测了抗汉赛巴尔通体的免疫球蛋白G类抗体。对53名已确诊淋巴结病的儿童，采用针对汉赛巴尔通体的间接免疫荧光法检测IgG抗体。在53名受检者中，29名（55%）儿童检测结果为阳性。在23名IgG抗体检测结果为阴性的儿童中，9名儿童进行了复查。其中5名（56%）儿童复查结果显示IgG抗体相对于首次检测有所增加。由于抗汉赛巴尔通体特异性IgG抗体的出现频率较高，猫抓病应被视为儿童淋巴结病的一个病因。如果检测结果为阴性，在儿童淋巴结病的病因中汉赛巴尔通体仍有可能存在，应在首次检测后的10 - 21天进行第二次检测。
