Podsiadły Edyta, Sokołowska Edyta, Tylewska-Wierzbanowska Stanisława
Przegl Epidemiol. 2002;56(3):399-407.
Bartonella henselae and Bartonella quintana infections result in illnesses with symptoms of severity ranging from mild lymphadenopathy (CSD) to systemic disease. The aim of the study was to estimate a prevalence of B. henselae and B. quintana infections in human in Poland. Serum samples collected from 265 patients in 1998-2001 were tested for the presence of antibodies specific to B. henselae and B. quintana. Levels of serum IgM and IgG antibodies to Bartonella henselae and Bartonella quintana were measured with indirect microimmunofluorescence test (MRL Diagnostic, USA). Cats' sera were assessed with indirect microimmunofluorescence test (MRL Diagnostic, USA) and goat immune serum anti-cat IgG FITC conjugate (Sigma, USA). Bartonella henselae specific antibodies were detected in 146 (57.0%) patients with lymphadenopathy. From that number 11.3% have shown specific Bartonella henselae IgM serum antibodies. Bartonella quintana infection was detected with serological methods in 4 patients. It has been found that CSD is a seasonal infection, with most cases occurring in autumn. Most cases of the disease have been recognized in children 8-16 years old. Most of CSD cases (30.1%) were detected in Mazowieckie voivodeship. There were no cases of CSD in Pomorskie, Podkarpackie, Lubuskie and Opolskie voivodeship. The seroprevalence of Bartonella sp. infections in cats was estimated on 86% (31/36). The highest titer of specific Bartonella henselae antibodies detected in cats was 1024. The number of detected Bartonella henselae infections in Poland is very low. It is very probable that the number of cases is underestimated in our country. Cat scratch disease is the most frequently clinically and serologically identified bartonellosis.
亨氏巴尔通体和五日热巴尔通体感染会引发一系列疾病，症状严重程度从轻度淋巴结病（猫抓病）到全身性疾病不等。本研究的目的是评估波兰人群中亨氏巴尔通体和五日热巴尔通体感染的患病率。1998年至2001年期间从265名患者采集的血清样本，检测其中是否存在针对亨氏巴尔通体和五日热巴尔通体的特异性抗体。采用间接微量免疫荧光试验（美国MRL诊断公司）检测血清中针对亨氏巴尔通体和五日热巴尔通体的IgM和IgG抗体水平。猫血清采用间接微量免疫荧光试验（美国MRL诊断公司）以及山羊抗猫IgG FITC偶联免疫血清（美国西格玛公司）进行评估。在146名（57.0%）淋巴结病患者中检测到了亨氏巴尔通体特异性抗体。其中11.3%的患者血清中出现了特异性的亨氏巴尔通体IgM抗体。通过血清学方法在4名患者中检测到五日热巴尔通体感染。研究发现猫抓病是一种季节性感染疾病，大多数病例发生在秋季。该疾病的大多数病例在8至16岁的儿童中被确诊。猫抓病的大多数病例（30.1%）在马佐夫舍省被检测到。在滨海省、喀尔巴阡省、卢布斯卡省和奥波莱省未发现猫抓病病例。估计猫中巴尔通体属感染的血清阳性率为86%（31/36）。在猫中检测到的亨氏巴尔通体特异性抗体的最高滴度为1024。波兰检测到的亨氏巴尔通体感染病例数量非常少。很可能我国的病例数量被低估了。猫抓病是临床上和血清学上最常确诊的巴尔通体病。
