Takayama K, Nagata N, Miyagawa Y, Hirano H, Shigematus N
Research Institute for Diseases of the Chest, Faculty of Medicine, Kyushu University, Fukuoka.
Nihon Kyobu Shikkan Gakkai Zasshi. 1991 Jul;29(7):849-53.
The authors analyzed a total of 132 cases clinically diagnosed as sarcoidosis from 1979 to 1990. Routine TBLB sections revealed sarcoid granulomas in 57 cases (Stage 0; 5%, Stage 1; 40%, Stage 2; 57%). In 75 cases in whom routine sections did not show granuloma, we prepared additional sections from paraffin-embedded blocks as step sections. When examined with step sections in addition to routine specimens, the detection rate of sarcoid granuloma increased to 47% in Stage 1 and 82% in Stage 2. We concluded that making step sections of TBLB specimens is a useful diagnostic method in cases suspected of sarcoidosis, especially in Stage 2 cases.
作者分析了1979年至1990年间临床诊断为结节病的132例病例。常规经支气管肺活检（TBLB）切片显示57例有结节病肉芽肿（0期；5%，1期；40%，2期；57%）。在75例常规切片未显示肉芽肿的病例中，我们从石蜡包埋块制备额外切片作为连续切片。当除常规标本外还用连续切片检查时，1期结节病肉芽肿的检出率增至47%，2期增至82%。我们得出结论，对TBLB标本制作连续切片是疑似结节病病例，尤其是2期病例的一种有用诊断方法。
