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遗传性乳腺癌/卵巢癌高危家庭决策的预测因素

Predictors of decision making in families at risk for inherited breast/ovarian cancer.

作者信息

Mellon Suzanne, Janisse James, Gold Robin, Cichon Michelle, Berry-Bobovski Lisa, Tainsky Michael A, Simon Michael S

机构信息

College of Health Professions, University of Detroit Mercy, Detroit, MI 48221-3038, USA.

出版信息

Health Psychol. 2009 Jan;28(1):38-47. doi: 10.1037/a0012714.

Abstract

OBJECTIVE

The purpose of this study was to identify factors associated with decision making about inherited cancer risk information within families and determine the interdependence between survivors' and relatives' decision making.

DESIGN

A descriptive, cross-sectional design using a population-based sample of 146 dyads (N = 292) was used. Analyses included multilevel modeling using the Actor-Partner-Interdependence Model.

MAIN OUTCOME MEASURES

Decision making regarding inherited cancer risk information.

RESULTS

Several individual and family factors contributed toward survivors' and female relatives' decision making about inherited cancer risk information. Individual factors included the individual's perceptions of their family communication and cancer history. Family factors included survivors' and family members' age, communication and coping style that influenced the decision making of the other member of the dyad. Cancer worries and a monitoring coping style affected both seeking and avoiding decision making for survivors and relatives.

CONCLUSIONS

In view of the importance of genetic information upon family health outcomes, it is critical to address both individual and family factors that may influence decision making about cancer risk information and surveillance options for all members within the family.

摘要

目的

本研究旨在确定与家庭中遗传性癌症风险信息决策相关的因素,并确定幸存者和亲属决策之间的相互依存关系。

设计

采用描述性横断面设计,以146对(N = 292)基于人群的样本为研究对象。分析包括使用行为者-伙伴相互依存模型的多层次建模。

主要观察指标

关于遗传性癌症风险信息的决策。

结果

几个个体和家庭因素影响了幸存者和女性亲属对遗传性癌症风险信息的决策。个体因素包括个体对其家庭沟通和癌症病史的认知。家庭因素包括幸存者和家庭成员的年龄、沟通方式和应对方式,这些因素会影响二元组中另一名成员的决策。癌症担忧和监测应对方式对幸存者和亲属寻求和避免决策均有影响。

结论

鉴于遗传信息对家庭健康结果的重要性,解决可能影响癌症风险信息决策和家庭所有成员监测选择的个体和家庭因素至关重要。

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