Favrolt N, Bonniaud P, Cercueil J-P, Logerot S, Foucher P, Camus C, Camus P
Service de Pneumologie et Réanimation Respiratoire, CHU de Dijon, France.
Rev Mal Respir. 2009 Jan;26(1):74-7. doi: 10.1016/s0761-8425(09)70138-x.
Symptomatic complications can occur after intravascular injection of cyanoacrylate glue. We report a case of pulmonary embolism following embolisation of an arteriovenous malformation (AVM).
A 46-year-old woman was found to have an internal iliac AVM which was obliterated using N-butyl-2 cyanoacrylate (NBCA) mixed with lipiodol. The early clinical course was uneventful. On the third post-operative day she complained of sudden, transient chest tightness. On admission one hour later the chest pain had disappeared. Physical examination was normal. A chest roentgenogram showed multiple, dense, branched opacities scattered throughout both lung fields which were confirmed on HRCT, suggesting diffuse scattered embolism of iodine- labelled NBCA. The radiological signs persisted 6 months later.
Endovascular treatment of arteriovenous malformations with NBCA can be responsible for symptomatic pulmonary embolism. This is not detectable radiologically in the absence of contrast medium. Radiologists should be aware of these often asymptomatic, but sometimes fatal, embolic complications.
血管内注射氰基丙烯酸酯胶水后可能会出现症状性并发症。我们报告一例动静脉畸形(AVM)栓塞术后发生肺栓塞的病例。
一名46岁女性被发现患有髂内动静脉畸形,使用与碘油混合的正丁基-2-氰基丙烯酸酯(NBCA)将其闭塞。早期临床过程平稳。术后第三天,她抱怨突然出现短暂的胸闷。一小时后入院时胸痛已消失。体格检查正常。胸部X线片显示两肺野散在多个密集、分支状的不透光区,高分辨率CT(HRCT)证实了这一点,提示碘标记的NBCA发生弥漫性散在栓塞。6个月后放射学征象仍持续存在。
用NBCA对动静脉畸形进行血管内治疗可能导致症状性肺栓塞。在没有造影剂的情况下,这在放射学上无法检测到。放射科医生应意识到这些通常无症状但有时致命的栓塞并发症。