Heuer M, Frühauf N R, Treckmann J, Witzke O, Paul A, Kaiser G M
Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Universitätsklinikum Essen, Universität Duisburg-Essen.
Dtsch Med Wochenschr. 2009 Feb;134(9):412-6. doi: 10.1055/s-0028-1124009. Epub 2009 Feb 11.
Kidney transplantation is the best therapeutic option in many patients with end-stage renal disease, because it significantly increases lifespan over that of patients who remain on dialysis. Because of organ shortage the average waiting time for a suitable kidney in Germany is about four years after the onset of dialysis treatment. Currently about 80% of all transplanted kidneys are obtained from brain-dead patients. The possibility for kidney transplantation after living donation reduces the minimum waiting time to a few weeks. An optimized organizational strategy as well as donor and recipient preparation are possible in living donation, resulting in excellent transplant quality and a short cold-ischemia time. Pre-emptive kidney transplantation after living donation is an attractive treatment option without the need for previous dialysis and is also an option for children. The excellent long-term results after kidney transplantation have been caused by improvement of operative technique, organizational strategy, donor preparation, postoperative care and, in particular, immunosuppression.
肾移植是许多终末期肾病患者的最佳治疗选择,因为与维持透析的患者相比,肾移植能显著延长患者寿命。由于器官短缺,德国患者开始透析治疗后等待合适肾脏的平均时间约为四年。目前,所有移植肾中约80%来自脑死亡患者。活体供肾肾移植可将最短等待时间缩短至几周。活体供肾肾移植可以采用优化的组织策略以及供体和受体准备,从而获得优异的移植质量和较短的冷缺血时间。活体供肾肾移植后的抢先肾移植是一种有吸引力的治疗选择,无需先前进行透析,也是儿童的一种选择。肾移植术后优异的长期效果得益于手术技术、组织策略、供体准备、术后护理尤其是免疫抑制的改善。