Nagy Agnes, Vörös Viktor, Tényi Tamás
Pszichiátriai és Pszichoterápiás Klinika, Pécsi Tudományegyetem, Pécs.
Neuropsychopharmacol Hung. 2008 Oct;10(4):213-24.
INTRODUCTION, AIMS: The authors present the Cotard's syndrome, a rare psychiatric condition, pointing out the latest results in terms of etiology and psychoneurology. The central feature of the syndrome is a nihilistic delusion, in which the patient denies his or her own existence and that of the external world.
We searched electronic databases using the appropriate search terms, relevant articles were carefully reviewed. We present three cases from our clinical practice.
After the overview of the latest biological and neuropsychological findings, the historical aspects of the condition, the terminology, the nosology, the classification, the differential diagnostics and the etiology are discussed. The psychopathology and the phenomenology of Cotard's syndrome are also presented, shedding light on existential aspects as well. To sum up with useful information for the clinical practice, the possible treatment strategies, the course and the prognosis of the disease are also discussed.
The presented theoretical and practical aspects give a lead on deeper understanding, easier recognition and more adequate therapy of the Cotard's syndrome.
引言、目的：作者介绍科塔尔综合征，一种罕见的精神疾病，指出病因学和精神神经学方面的最新研究结果。该综合征的核心特征是虚无妄想，患者否认自身及外部世界的存在。
我们使用适当的检索词搜索电子数据库，并仔细审阅相关文章。我们展示了来自临床实践的三个病例。
在概述最新的生物学和神经心理学研究结果之后，讨论了该疾病的历史背景、术语、疾病分类学、分类、鉴别诊断和病因。还介绍了科塔尔综合征的精神病理学和现象学，也揭示了其存在主义方面。为总结对临床实践有用的信息，还讨论了可能的治疗策略、疾病进程和预后。
所呈现的理论和实践方面有助于更深入地理解、更易于识别并更充分地治疗科塔尔综合征。
