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使用新型微剥脱二氧化碳激光进行皮肤剥脱性重建。

Ablative skin resurfacing with a novel microablative CO2 laser.

作者信息

Gotkin Robert H, Sarnoff Deborah S, Cannarozzo Giovanni, Sadick Neil S, Alexiades-Armenakas Macrene

出版信息

J Drugs Dermatol. 2009 Feb;8(2):138-44.

Abstract

Carbon dioxide (CO2) laser skin resurfacing has been a mainstay of facial rejuvenation since its introduction in the mid 1990s. Recently, a new generation of fractional or microablative CO2 lasers has been introduced to the marketplace. According to the concept of fractional photothermolysis, these lasers ablate only a fraction of the epidermal and dermal architecture in the treatment area. An array of microscopic thermal wounds is created that ablates the epidermis and dermis within very tiny zones; adjacent to these areas, the epidermis and dermis are spared. This microablative process of laser skin resurfacing has proven safe and effective not only for facial rejuvenation, but elsewhere on the body as well. It is capable of improving wrinkles, acne scars, and other types of atrophic scars and benign pigmented lesions associated with elastotic, sun-damaged skin. Because of the areas of spared epidermis and dermis inherent in a procedure that employs fractional photothermolysis, healing is more rapid compared to fully ablative CO2 laser skin resurfacing and downtime is proportionately reduced. A series of 32 consecutive patients underwent a single laser resurfacing procedure with the a new microablative CO2 laser. All patients were followed for a minimum of 6 months and were asked to complete patient satisfaction questionnaires; a 6 month postoperative photographic evaluation by an independent physician, not involved in the treatment, was also performed. Both sets of data were graded and reported on a quartile scale. Results demonstrated greater than 50% improvement in almost all patients with those undergoing treatment for wrinkles, epidermal pigment or solar elastosis deriving the greatest change for the better (>75%).

摘要

自20世纪90年代中期引入以来,二氧化碳(CO₂)激光皮肤磨削术一直是面部年轻化的主要手段。最近,新一代的分次或微剥脱性CO₂激光已投放市场。根据分次光热解的概念,这些激光仅剥脱治疗区域内表皮和真皮结构的一部分。会形成一系列微小的热损伤区,在非常小的区域内剥脱表皮和真皮;在这些区域相邻处,表皮和真皮得以保留。这种激光皮肤磨削术的微剥脱过程已被证明不仅对面部年轻化安全有效,对身体其他部位也同样如此。它能够改善皱纹、痤疮瘢痕以及其他类型的萎缩性瘢痕和与弹性组织变性、日光损伤皮肤相关的良性色素性病变。由于采用分次光热解的手术中存在表皮和真皮保留区域,与完全剥脱性CO₂激光皮肤磨削术相比,愈合更快,停工期也相应缩短。连续32例患者接受了一次使用新型微剥脱性CO₂激光的激光磨削手术。所有患者至少随访6个月,并被要求完成患者满意度调查问卷;还由一名未参与治疗的独立医生进行了术后6个月的照片评估。两组数据均按四分位数量表进行分级和报告。结果显示,几乎所有接受皱纹、表皮色素或日光性弹性组织变性治疗的患者改善率均超过50%,其中改善最为明显(>75%)。

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