[干扰素对淋巴细胞有丝分裂的抑制作用]
[Interferon inhibition of lymphocyte mitogenesis].
作者信息
Brodeur B R, Weinstein Y, Melnon K L, Merigan C
出版信息
Ann Immunol (Paris). 1977 Jan-Mar;128(1-2):53-6.
PMID:192133
Abstract
Interferon inhibits the early phase of mitogenic action of concanavalin A on lymphocytes. There was no evidence for a role of cyclic AMP in the process of inhibition. Dialysis of interferon against high salt and urea did not separate cell inhibitory activity from antiviral activity.
摘要
干扰素抑制伴刀豆球蛋白A对淋巴细胞促有丝分裂作用的早期阶段。没有证据表明环磷酸腺苷在这一抑制过程中发挥作用。用高盐和尿素对干扰素进行透析，并未将细胞抑制活性与抗病毒活性分开。
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